L-2-Amino-3-guanidinopropionic acid hydrochloride
L-2-Amino-3-guanidinopropionic acid hydrochloride (CAS: 1482-99-1; Formula: C4H10N4O2 · HCl) is a valuable unnatural amino acid derivative. With a molecular weight of 182.61 g/mol, it serves as a critical building block in peptide synthesis and chemical biology research. Its structure, related to arginine, makes it useful for creating modified peptides and probing biological pathways. This compound is supplied by Tech Serve Solutions for laboratory and research applications.
- IUPAC
- L-α-Amino-β-guanidinopropionic acid hydrochloride
- Synonyms
- L-α-Amino-β-guanidinopropionic acid hydrochloride

Peptide Synthesis
L-2-Amino-3-guanidinopropionic acid hydrochloride is utilised as a non-canonical amino acid in solid-phase and solution-phase peptide synthesis. It allows for the introduction of modified side chains to explore structure-activity relationships.
Chemical Biology Research
This compound serves as a tool in chemical biology to investigate enzyme mechanisms, protein interactions, and metabolic pathways. Its structural similarity to arginine enables its use in competitive inhibition studies.
Chemical Synthesis
As a versatile intermediate, it finds application in the synthesis of more complex organic molecules and novel chemical entities. Its guanidino group and amino acid backbone offer multiple reaction sites.
Unnatural Amino Acid Studies
It is employed in the study of unnatural amino acids and their incorporation into peptides or proteins. This facilitates the development of peptides with novel functionalities or altered biochemical properties.
| Molecular weight | 182.61 |
|---|---|
| Empirical formula | C4H10N4O2 · HCl |
| Storage temperature | 2-8°C |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-2-Amino-3-guanidinopropionic acid hydrochloride used for?
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L-2-Amino-3-guanidinopropionic acid hydrochloride is primarily used in peptide synthesis, chemical biology research, general chemical synthesis, and studies involving unnatural amino acids.
What are the CAS number and formula for L-2-Amino-3-guanidinopropionic acid hydrochloride?
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The CAS number is 1482-99-1, and the chemical formula is C4H10N4O2 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-2-Amino-3-guanidinopropionic acid hydrochloride for research and laboratory use. The specific assay and purity information can be found on the product's Certificate of Analysis, which is available upon request. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling precautions for this product?
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This compound is classified as an irritant, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It is recommended to wear a dust mask (type N95 US), eyeshields, and gloves. Ensure adequate ventilation and avoid breathing dust. In case of eye contact, rinse cautiously with water for several minutes and seek medical attention.
How is L-2-Amino-3-guanidinopropionic acid hydrochloride shipped and exported?
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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping regulations. Packaging is designed to ensure product integrity and safety during transit. Please contact us for specific international shipping details.
How can I request a sample or a quote for L-2-Amino-3-guanidinopropionic acid hydrochloride?
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To request a sample or a quote, please use the contact form on our website or email our sales department, providing the product name and CAS number (1482-99-1).
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