3,5-Difluoro-4-formylphenylboronic acid
3,5-Difluoro-4-formylphenylboronic acid (CAS 870718-11-9) is a fluorinated aromatic boronic acid with a molecular weight of 185.92 g/mol. This compound functions as a key intermediate and building block in organic synthesis. Its structure, featuring both a boronic acid moiety and an aldehyde group, makes it valuable for cross-coupling reactions and the construction of complex organic molecules, particularly in pharmaceutical research and materials science.
- IUPAC
- 3,5-Difluoro-4-formylbenzeneboronic acid
- Synonyms
- 3,5-Difluoro-4-formylphenylboronic acidC6H2F2CHOB(OH)23,5-Difluoro-4-formylbenzeneboronic acid
Synthesis of Kinase Inhibitors
Used as a reactant in the preparation of pyrazolopyrimidinamine derivatives, which are investigated as potent tyrosine and phosphoinositide kinase inhibitors for therapeutic applications.
Development of Glucose Sensors
Serves as a precursor in the preparation of boronate-based sensors, specifically designed for the detection and measurement of D-glucose concentrations.
Organic Synthesis Building Block
This difluorinated phenylboronic acid derivative is a versatile building block for introducing fluorinated aromatic aldehyde functionalities into target molecules via various synthetic transformations.
| Molecular weight | 185.92 |
|---|---|
| Linear formula | C6H2F2CHOB(OH)2 |
| Assay | ≥95% |
| Application | Reactant for:• Preparation of pyrazolopyrimidinamine derivatives as tyrosine and phosphinositide kinase inhibitors1• Preparation of boronate based D-glucose sensors2 |
| Melting point | 255-260 °C |
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 3,5-Difluoro-4-formylphenylboronic acid used for?
+
3,5-Difluoro-4-formylphenylboronic acid is primarily used as a reactant in the preparation of pyrazolopyrimidinamine derivatives for kinase inhibition and in the synthesis of boronate-based D-glucose sensors. It also serves as a general organic building block in chemical synthesis.
What are the CAS number and molecular formula for this compound?
+
The CAS number is 870718-11-9 and the linear molecular formula is C6H2F2CHOB(OH)2.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies 3,5-Difluoro-4-formylphenylboronic acid with an assay of ≥95%. This is a technical/research grade material and TSS does not represent it as USP, BP, EP, or other pharmacopoeia standards.
How should 3,5-Difluoro-4-formylphenylboronic acid be handled safely?
+
When handling, it is recommended to use a dust mask type N95 (US), eyeshields, and gloves. Ensure adequate ventilation. The compound has a WGK rating of 3 in Germany, indicating a high hazard to water.
Is this compound hazardous?
+
While specific GHS hazards are not detailed in the provided data, boronic acids can be irritants. Refer to the Safety Data Sheet (SDS) for comprehensive hazard information. Appropriate personal protective equipment including a dust mask, eyeshields, and gloves should be used.
How can I request a quote or sample?
+
To request a quote or a sample of 3,5-Difluoro-4-formylphenylboronic acid, please contact our sales team through the website or by phone.
Does Tech Serve Solutions export this chemical?
+
Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, including 3,5-Difluoro-4-formylphenylboronic acid.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis