L-4-Hydroxyproline methyl ester hydrochloride
L-4-Hydroxyproline methyl ester hydrochloride (CAS: 40216-83-9), with the molecular formula C6H11NO3 · HCl and a molecular weight of 181.62, is a valuable derivative of hydroxyproline. It serves as a key building block in peptide synthesis and is utilized in various chemical biology and synthesis applications. This compound offers a protected form of the amino acid, facilitating controlled reactions and the creation of complex peptide structures.
Peptide Synthesis
L-4-Hydroxyproline methyl ester hydrochloride is employed as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis. Its ester and hydrochloride functionalities allow for selective deprotection and coupling steps in the construction of peptides containing hydroxyproline residues.
Chemical Biology Research
This compound is utilised in chemical biology for the synthesis of modified peptides and peptidomimetics. It aids in probing biological systems and developing novel therapeutic agents where specific proline or hydroxyproline modifications are required.
Organic Synthesis Intermediate
As a functionalised proline derivative, it acts as an intermediate in broader organic synthesis. Researchers use it to introduce the 4-hydroxyproline motif into diverse molecular scaffolds for various chemical research endeavours.
| Molecular weight | 181.62 |
|---|---|
| Empirical formula | C6H11NO3 · HCl |
| Assay | ≥98.0% (TLC) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-4-Hydroxyproline methyl ester hydrochloride used for?
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L-4-Hydroxyproline methyl ester hydrochloride is primarily used as a protected building block in peptide synthesis, chemical biology research, and as an intermediate in organic synthesis.
What are the CAS number and molecular formula for L-4-Hydroxyproline methyl ester hydrochloride?
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The CAS number is 40216-83-9, and its molecular formula is C6H11NO3 · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-4-Hydroxyproline methyl ester hydrochloride with an assay of ≥98.0% as determined by TLC. This product is supplied for research and development purposes and is not represented as USP, BP, or EP grade.
How should L-4-Hydroxyproline methyl ester hydrochloride be handled safely?
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When handling, it is essential to wear safety eyewear and gloves. A type N95 (US) or type P1 (EN143) respirator filter should be used for respiratory protection. The substance is classified with WGK Germany 3.
Is L-4-Hydroxyproline methyl ester hydrochloride available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals, and L-4-Hydroxyproline methyl ester hydrochloride can be shipped internationally.
How can I request a quote or sample?
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To request a quote or a sample of L-4-Hydroxyproline methyl ester hydrochloride, please contact our sales team through the website or by phone.
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