L-(+)-2-Amino-4-phosphonobutyric acid
L-(+)-2-Amino-4-phosphonobutyric acid (CAS: 23052-81-5; Formula: C4H10NO5P) is a selective agonist for metabotropic glutamate receptors. This white crystalline solid has a molecular weight of 183.10 g/mol. It finds primary applications in biochemical research, particularly in studies related to cell signaling, neuroscience, and the function of excitatory amino acid receptors. Its specific activity makes it a valuable tool for understanding neurological pathways.
- IUPAC
- L-AP-4,L-AP4
- Synonyms
- L-AP-4L-AP4

Neuroscience Research
L-(+)-2-Amino-4-phosphonobutyric acid serves as a tool for investigating the roles of metabotropic glutamate receptors in neuronal function and synaptic transmission. It is used to study excitatory neurotransmission and its modulation.
Biochemical Studies
This compound is utilised in biochemical assays to explore cellular signaling pathways, particularly those involving GPCRs. Its specificity allows for targeted investigations into receptor-ligand interactions.
Cell Biology Investigations
Researchers employ L-(+)-2-Amino-4-phosphonobutyric acid to study cellular responses and mechanisms within the fields of cell biology and membrane protein function. It aids in understanding receptor activation and downstream effects.
| Molecular weight | 183.10 |
|---|---|
| Empirical formula | C4H10NO5P |
| Optical purity | optical purity: ≥95% (HPLC, Marfey′s reagent) |

Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-(+)-2-Amino-4-phosphonobutyric acid used for?
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L-(+)-2-Amino-4-phosphonobutyric acid is used in neuroscience and biochemical research as a selective agonist for metabotropic glutamate receptors, aiding in the study of cell signaling and neurotransmission.
What is the CAS number and chemical formula for L-(+)-2-Amino-4-phosphonobutyric acid?
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The CAS number is 23052-81-5 and the empirical formula is C4H10NO5P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies L-(+)-2-Amino-4-phosphonobutyric acid with an optical purity of ≥95% (HPLC, Marfey's reagent). TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for L-(+)-2-Amino-4-phosphonobutyric acid?
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This compound is a Warning substance, causing skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, should be worn. Ensure adequate ventilation.
How is L-(+)-2-Amino-4-phosphonobutyric acid shipped?
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As a global supplier and exporter of fine chemicals, Tech Serve Solutions ensures appropriate packaging and documentation for the safe and compliant shipment of L-(+)-2-Amino-4-phosphonobutyric acid worldwide.
How can I request a sample or quote for L-(+)-2-Amino-4-phosphonobutyric acid?
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To request a sample or a quotation, please contact our sales department via the website or provide your details through the designated portal.
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