2-Methoxy-3-(trifluoromethyl)pyridine
2-Methoxy-3-(trifluoromethyl)pyridine (CAS: 121643-44-5), with the molecular formula C7H6F3NO and a molecular weight of 177.12 g/mol, is a heterocyclic organic compound. This pyridine derivative is recognised for its utility as a building block in chemical synthesis. Its trifluoromethyl group and methoxy substituent provide unique reactivity, making it valuable in the development of novel chemical entities for research and industrial applications.

Organic Synthesis
Utilised as a key intermediate in the synthesis of complex organic molecules. The trifluoromethyl and methoxy groups on the pyridine ring offer specific reaction sites for further functionalisation.
Pharmaceutical Research
Serves as a building block in the development of new pharmaceutical agents. Its structure can be incorporated into candidate molecules for drug discovery programmes.
Agrochemical Development
A potential intermediate in the synthesis of novel agrochemicals. The unique electronic properties conferred by the trifluoromethyl group can be advantageous in designing new crop protection agents.
Materials Science
Can be employed in the synthesis of specialised materials where fluorinated heterocyclic motifs are desired for specific electronic or physical properties.
| Molecular weight | 177.12 |
|---|---|
| Empirical formula | C7H6F3NO |
| Assay | 96% |
| Density | 1.297 g/mL at 25 °C |
| Refractive index | n20/D 1.441 |


Hazard statements
- H226Flammable liquid and vapour
- H300Fatal if swallowed
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P264Wash thoroughly after handling
- P301IF SWALLOWED
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 47 °C / 116.6 °F |
| Transport (UN / ADR) | UN 1992 3/PG 3 |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 10-25-36/37/38 |
| Safety statements (S) | 16-26-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2-Methoxy-3-(trifluoromethyl)pyridine primarily used for?
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2-Methoxy-3-(trifluoromethyl)pyridine is primarily used as a building block in organic synthesis, particularly in the development of pharmaceuticals and agrochemicals.
What is the CAS number and formula for this compound?
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The CAS number is 121643-44-5, and its molecular formula is C7H6F3NO.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2-Methoxy-3-(trifluoromethyl)pyridine with an assay of 96%. It is supplied as a technical or research grade chemical and is not represented as USP, BP, EP, or any other pharmacopoeia standard.
How should 2-Methoxy-3-(trifluoromethyl)pyridine be handled safely?
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This compound is classified as Danger, with hazards including flammability (H226), acute toxicity (H300), and irritation (H315, H319, H335). Handle with appropriate personal protective equipment, including eyeshields, gloves, and a suitable respirator, in a well-ventilated area. Keep away from heat and open flames.
Is this chemical suitable for export or international shipping?
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Yes, Tech Serve Solutions is an experienced global supplier and exporter of fine chemicals, including 2-Methoxy-3-(trifluoromethyl)pyridine, adhering to all international shipping regulations (UN 1992 3/PG 3).
How can I request a quote or sample?
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To request a quote or a sample, please contact our sales team through the dedicated enquiry form on our website or call us directly.
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