Ki8751 hydrate
Ki8751 hydrate (CAS: 228559-41-9 anhydrous) is a chemical compound with the formula C24H18F3N3O4 · xH2O. It presents as a white solid with a molecular weight of 469.41 on an anhydrous basis. This compound is primarily utilised in scientific research, particularly within the fields of cell biology and kinase/phosphatase biology, serving as a valuable tool for investigating cellular signalling pathways and receptor tyrosine kinase inhibition. Its solubility in DMSO is greater than 20 mg/mL.
- IUPAC
- 1-(2,4-Difluoro-phenyl)-3-[4-(6,7-dimethoxy-quinolin-4-yloxy)-2-fluoro-phenyl]-urea hydrate
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Research in Cell Biology
Ki8751 hydrate is employed in laboratory settings for cell biology research. Its properties make it suitable for studies investigating cellular processes and signalling mechanisms.
Kinase/Phosphatase Pathway Analysis
This compound is utilised in research focused on kinase and phosphatase biology. It can serve as a probe for understanding signalling cascades involving these enzymes.
Receptor Tyrosine Kinase Inhibition Studies
Ki8751 hydrate is relevant for research into receptor tyrosine kinase inhibitors. It can be used to explore the effects of inhibiting specific tyrosine kinases, including VEGFR.
Neuroscience and Cell Signaling Research
The compound finds application in neuroscience and broader cell signaling research, aiding in the exploration of complex biological pathways and molecular interactions.
| Molecular weight | 469.41 (anhydrous basis) |
|---|---|
| Empirical formula | C24H18F3N3O4 · xH2O |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
| Solubility | DMSO: >20 mg/mL |
| Storage temperature | −20°C |
Hazard statements
- H315Causes skin irritation
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-38 |
| Safety statements (S) | 37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ki8751 hydrate used for?
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Ki8751 hydrate is primarily used in scientific research, particularly within cell biology, cell signaling, neuroscience, and kinase/phosphatase biology. It is also relevant for studies involving receptor tyrosine kinase inhibitors.
What is the CAS number and molecular formula of Ki8751 hydrate?
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The CAS number for the anhydrous form is 228559-41-9, and the molecular formula is C24H18F3N3O4 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ki8751 hydrate with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, or EP grade.
How should Ki8751 hydrate be handled safely?
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Ki8751 hydrate is classified as a GHS07 warning substance with hazard statement H315 (Causes skin irritation). It is recommended to use a dust mask type N95 (US), eyeshields, and gloves when handling. For European markets, it is classified as Xn with risk statements R22-38 and safety statement S37.
Is Ki8751 hydrate a controlled substance?
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The provided data does not indicate that Ki8751 hydrate is a controlled substance.
How is Ki8751 hydrate shipped and exported?
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Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals and laboratory reagents, equipped to handle international shipments. Specific shipping and export details can be arranged upon request.
How can I request a sample or quote for Ki8751 hydrate?
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To request a sample or a quote for Ki8751 hydrate, please contact the Tech Serve Solutions sales team directly through our official channels.
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