L-(+)-2-Amino-6-phosphonohexanoic acid
L-(+)-2-Amino-6-phosphonohexanoic acid (CAS: 126253-57-4), with the molecular formula C6H14NO5P and a molecular weight of 211.15 g/mol, is a white solid compound. It functions as an antagonist for AMPA and kainate receptors, making it a valuable tool in neuroscience research. Its primary applications involve studying excitatory amino acid receptors and ionotropic glutamate receptor modulation.
- IUPAC
- L-AP6
- Synonyms
- L-AP6
Neuroscience Research
L-(+)-2-Amino-6-phosphonohexanoic acid serves as a selective antagonist for AMPA and kainate receptors. It is instrumental in investigating the roles of excitatory amino acids in synaptic transmission and neuronal excitability.
Cell Biology Studies
This compound is utilised in cell biology to probe the function of ionotropic glutamate receptors and ligand-gated ion channels. It aids in understanding cellular responses mediated by these receptor systems.
Neurotransmission Investigation
As a modulator of excitatory neurotransmission, L-(+)-2-Amino-6-phosphonohexanoic acid is employed to study the mechanisms governing neurotransmitter release and receptor activation in the central nervous system.
| Molecular weight | 211.15 |
|---|---|
| Empirical formula | C6H14NO5P |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is L-(+)-2-Amino-6-phosphonohexanoic acid used for?
+
L-(+)-2-Amino-6-phosphonohexanoic acid is used in neuroscience and cell biology research as a selective antagonist for AMPA and kainate receptors, aiding in the study of excitatory amino acid signaling, neurotransmission, and ionotropic glutamate receptor function.
What is the CAS number and formula for L-(+)-2-Amino-6-phosphonohexanoic acid?
+
The CAS number is 126253-57-4 and the molecular formula is C6H14NO5P.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies L-(+)-2-Amino-6-phosphonohexanoic acid with an assay of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How should L-(+)-2-Amino-6-phosphonohexanoic acid be handled safely?
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Handle L-(+)-2-Amino-6-phosphonohexanoic acid with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Avoid breathing dust and ensure adequate ventilation. This compound is classified as a Warning with hazards H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation).
How is this product packed, shipped, and exported?
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This product is typically supplied as a white solid. Tech Serve Solutions is a global supplier and exporter, adhering to all necessary regulations for safe and compliant international shipment.
How can I request a quote or sample?
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To request a quote or a sample of L-(+)-2-Amino-6-phosphonohexanoic acid, please contact our sales team through the website or by phone.
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