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Kynurenic acid

CAS 492-27-3C10H7NO3Cell Biology

Kynurenic acid (CAS: 492-27-3), with the molecular formula C10H7NO3 and a molecular weight of 189.17 g/mol, is a quinoline carboxylic acid derivative. It functions as an endogenous NMDA receptor antagonist and has been investigated for its roles in cellular signalling and neuroscience. Available from Tech Serve Solutions with an assay of ≥98%, it is suitable for research and laboratory applications.

IUPAC
4-Hydroxyquinoline-2-carboxylic acid
Synonyms
4-Hydroxyquinoline-2-carboxylic acid
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Kynurenic acid (C10H7NO3) — chemical structure, CAS 492-27-3; Life Science, fine chemical supplied by Tech Serve Solutions
AMPA/Kainate AntagonistsBioactive Small MoleculesCell BiologyExcitatory Amino AcidsIon ChannelsLigand-Gated Ion ChannelsNeuroscienceNeurotransmissionNeurotransmitters More...
01 /Applications

Neuroscience Research

Kynurenic acid is a vital tool in neuroscience research due to its role as an endogenous antagonist of NMDA and AMPA/kainate receptors. It is used to study excitatory neurotransmission and its implications in various neurological conditions.

Cell Biology Studies

As a bioactive small molecule, kynurenic acid finds application in cell biology for investigating signalling pathways and cellular responses. Its involvement in neuroprotection and neurodegenerative disease models makes it a key research compound.

Receptor Modulation Studies

This compound serves as a ligand-gated ion channel modulator, making it valuable for studies focused on ionotropic glutamate receptors. Researchers utilise it to probe receptor function and pharmacology.

02 /Properties
Molecular weight189.17
Empirical formulaC10H7NO3
Assay≥98%
Melting point275 °C (dec.)(lit.)
03 /Safety & handling
GHS hazard pictogram: Harmful / irritant (GHS07)
Harmful / irritant
Warning

Hazard statements

  • H315Causes skin irritation
  • H319Causes serious eye irritation
  • H335May cause respiratory irritation

Precautionary statements

  • P261Avoid breathing dust, fume, gas or vapours
  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Gloves
Water hazard class (WGK, DE)3
Hazard codes (EU)Xi
Risk statements (R)36/37/38
Safety statements (S)26-36

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry
CAS number
492-27-3
MDL number
MFCD00006753
PubChem substance
24277986
Beilstein registry
147451
05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Kynurenic acid used for?

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Kynurenic acid is primarily used in neuroscience and cell biology research. It acts as an endogenous antagonist of NMDA receptors and modulates ligand-gated ion channels, aiding in the study of excitatory neurotransmission and related neurological processes.

What are the CAS number and molecular formula for Kynurenic acid?

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Kynurenic acid has the CAS number 492-27-3 and the molecular formula C10H7NO3.

What grade and purity does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Kynurenic acid with an assay of ≥98%. We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.

How should Kynurenic acid be handled safely?

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Kynurenic acid is classified with GHS07 symbol and a 'Warning' signal word. It carries hazard statements H315 (Causes skin irritation), H319 (Causes serious eye irritation), and H335 (May cause respiratory irritation). Safe handling requires wearing eyeshields, gloves, a dust mask type N95 (US), and working in a well-ventilated area. Avoid breathing dust.

How is Kynurenic acid packed and exported?

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Kynurenic acid is available for export globally by Tech Serve Solutions. Specific packing details for shipment can be provided upon request, adhering to all relevant shipping regulations.

How can I request a sample or quote for Kynurenic acid?

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To request a sample or a quote for Kynurenic acid, please contact our sales team through the website or by phone, providing your specific requirements.

Need Kynurenic acid in a specific grade or volume?