Indan-5-sulfonyl chloride
Indan-5-sulfonyl chloride (CAS: 52205-85-3; C9H9ClO2S; MW: 216.68) is a reactive organic compound. As a sulfonyl chloride, it is primarily employed as a key building block in organic synthesis. Its structure, featuring an indane ring substituted with a sulfonyl chloride group, makes it valuable for introducing the indane-5-sulfonyl moiety into more complex molecules. This functionality is leveraged in the development of novel chemical entities.
- IUPAC
- 2,3-Dihydro-1H-indene-5-sulfonyl chloride
Organic Synthesis Intermediate
Indan-5-sulfonyl chloride serves as a versatile intermediate in the synthesis of various organic compounds. The sulfonyl chloride group readily reacts with nucleophiles such as amines, alcohols, and thiols, enabling the formation of sulfonamides, sulfonates, and thioesters.
Pharmaceutical Research
This compound is utilised in medicinal chemistry research for the creation of novel drug candidates. The indane scaffold is present in several biologically active molecules, and its functionalisation via the sulfonyl chloride group can lead to new therapeutic agents.
Material Science
The reactivity of Indan-5-sulfonyl chloride allows for its incorporation into polymers or functional materials, potentially modifying their properties. It can be used to introduce specific chemical functionalities for material modification or development.
| Molecular weight | 216.68 |
|---|---|
| Empirical formula | C9H9ClO2S |
| Assay | 97% |
| Melting point | 45-50 °C |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Flash point | >110 °C / >230 °F |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34 |
| Safety statements (S) | 26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Indan-5-sulfonyl chloride used for?
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Indan-5-sulfonyl chloride is used as a building block in organic synthesis, particularly for introducing the indane-5-sulfonyl group into other molecules. It is valuable in pharmaceutical research and potentially in material science applications.
What is the CAS number and formula for Indan-5-sulfonyl chloride?
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The CAS number for Indan-5-sulfonyl chloride is 52205-85-3, and its molecular formula is C9H9ClO2S.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Indan-5-sulfonyl chloride with an assay of 97%. This product is typically supplied as a technical or research grade; TSS does not represent it as USP, BP, or EP grade.
How should Indan-5-sulfonyl chloride be handled?
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Indan-5-sulfonyl chloride is classified as Danger with hazard statement H314 (causes severe skin burns and eye damage). Handle with appropriate personal protective equipment (P280), ensure good ventilation, and avoid contact with skin and eyes (P305 + P351 + P338). In case of exposure, seek immediate medical attention (P310).
Is Indan-5-sulfonyl chloride a controlled substance?
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The provided data does not indicate that Indan-5-sulfonyl chloride is a controlled substance.
How is Indan-5-sulfonyl chloride packaged and exported?
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Indan-5-sulfonyl chloride is shipped according to UN 3261, Class 8, Packing Group III regulations. TSS is a global supplier and exporter of fine chemicals.
How can I request a sample or quote for Indan-5-sulfonyl chloride?
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To request a sample or quote, please contact the TSS sales team through our website or by calling our customer service.
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