Guanfacine hydrochloride
Guanfacine hydrochloride (CAS 29110-48-3), with the molecular formula C9H9Cl2N3O · HCl and a molecular weight of 282.55, is a white crystalline solid. It is primarily recognized for its applications as an alpha-adrenergic agonist. This compound serves as a valuable research chemical and a potential therapeutic agent, particularly in neurological and cardiovascular research. Its defined chemical properties make it a subject of interest in various biochemical studies.
- IUPAC
- N (Aminoiminomethyl)-2,6-dichlorobenzeneacetamide

Adrenergic Receptor Research
Guanfacine hydrochloride acts as an alpha-adrenergic agonist, making it a valuable tool for studying the function and regulation of adrenergic receptors, particularly in neuroscience and cardiovascular research.
Neuroscience Research
Utilised in studies investigating neurotransmission and cellular signalling pathways within the central nervous system, aiding in the understanding of neurological processes.
Biochemical Investigations
Serves as a bioactive small molecule in biochemical assays and research, contributing to the characterisation of biological mechanisms and potential drug candidates.
| Molecular weight | 282.55 |
|---|---|
| Empirical formula | C9H9Cl2N3O · HCl |
| Assay | ≥98% (HPLC) |
| Colour | white |
| Solubility | H2O: soluble12 mg/mL at 60 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ADRA2A(150), ADRA2B(151), ADRA2C(152) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Guanfacine hydrochloride used for?
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Guanfacine hydrochloride is primarily used as a research chemical and a tool for studying adrenergic receptors, neurotransmission, and related biochemical pathways. It is also recognised as an approved therapeutic for certain medical conditions, though its use as a research reagent is distinct.
What are the CAS number and formula for Guanfacine hydrochloride?
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The CAS number for Guanfacine hydrochloride is 29110-48-3, and its empirical formula is C9H9Cl2N3O · HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Guanfacine hydrochloride with a purity of ≥98% (HPLC). We do not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Guanfacine hydrochloride be handled safely?
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When handling Guanfacine hydrochloride, it is essential to use appropriate personal protective equipment, including eyeshields and gloves. A respirator with a P1 (EN143) or N95 (US) filter is recommended. The substance is classified with a WGK Germany of 3, indicating a high hazard to water.
Is Guanfacine hydrochloride a controlled substance?
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The provided data does not indicate that Guanfacine hydrochloride is a controlled substance.
How is Guanfacine hydrochloride typically packed and shipped?
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Guanfacine hydrochloride is typically packed securely for transit and exported by Tech Serve Solutions in compliance with international shipping regulations for chemical substances.
How can I request a quote or sample of Guanfacine hydrochloride?
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To request a quote or a sample of Guanfacine hydrochloride, please contact our sales team through the website or provide your details via the enquiry form.
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