Tech Serve Solutions

Guanidine hydrochloride

CAS 50-01-1NH2C(=NH)NH2 · HClBiochemicals & Reagents

Guanidine hydrochloride (CAS 50-01-1), molecular formula NH2C(=NH)NH2 · HCl, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to pharmacopoeia specification (USP, BP, EP). Every batch is tested and ships with a Certificate of Analysis; MSDS and technical data sheets are available on request. Tech Serve Solutions has supplied laboratory reagents, fine chemicals and pharmaceutical intermediates worldwide since 1998.

IUPAC
Aminoformamidine hydrochloride,Aminomethanamidine hydrochloride,Guanidinium chloride
Guanidine hydrochloride
BiochemicalsBiochemicals and ReagentsBuffers / Buffer SaltsChaotropic AgentsCore BioreagentsDNA & RNA PurificationDenaturationGeneral ReagentsHIS-Select
01 /Properties
Molecular weight95.53
Linear formulaNH2C(=NH)NH2 · HCl
Assay≥99.0%
Gradefor molecular biology
Density1.18 g/mL at 25 °C(lit.)
Refractive indexn20/D 1.465
SolubilityH2O: soluble6 M at 20 °C, clear, colorless
Melting point180-185 °C(lit.)
pH4.5-6.0 (25 °C, 6 M in H2O)
Concentration8 M in H2O (filtered)
Loss on drying≤0.05% loss on drying, 20 °C (HV)
Impurities testedDNases, none detectedRNases, none detectedinsoluble matter, passes filter testphosphatases, none detectedproteases, none detected
ApplicationStrong chaotropic agent useful for the denaturation and subsequent refolding of proteins. This strong denaturant can solubilize insoluble or denatured proteins such as inclusion bodies. This can be used as the first step in refolding proteins or enzymes into their active form. Urea and dithiothreitol (DTT) may also be necessary.
02 /Safety & handling
Harmful / irritant
Harmful / irritant
Warning

Hazard statements

  • H302Harmful if swallowed
  • H315Causes skin irritation
  • H319Causes serious eye irritation

Precautionary statements

  • P305IF IN EYES
Protective equipmentdust mask type N95 (US), Eyeshields, Faceshields, Gloves
Water hazard class (WGK, DE)1
Hazard codes (EU)Xn
Risk statements (R)22-36/38
Safety statements (S)22
Anion tracessulfate (SO42-): ≤50 mg/kg
Ignition residue≤0.05% (as SO4)

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

03 /Identifiers & registry
CAS number
50-01-1
MDL number
MFCD00013026
PubChem substance
24895119
Beilstein registry
3591990
04 /Additional specifications
Quality LevelELITE
Foreign ActivityDNase, RNase, none detected
Uv Absorptionλ: 260 nm Amax: 0.03λ: 280 nm Amax: 0.02
05 /Quality & supply

Documentation

Supplied to USP, BP and EP standards. Every batch ships with a Certificate of Analysis (assay, identity, purity); MSDS and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Guanidine hydrochloride?

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Guanidine hydrochloride (CAS 50-01-1), molecular formula NH2C(=NH)NH2 · HCl, is a high-purity chemical supplied by Tech Serve Solutions for biochemicals & reagents applications, to USP, BP and EP standards.

What grades of Guanidine hydrochloride does Tech Serve Solutions supply?

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Tech Serve Solutions supplies Guanidine hydrochloride in USP, BP, EP and reagent/AR grades. Custom specifications for nutraceutical or specialty pharmaceutical applications are available — contact our technical sales team.

What is the CAS number and molecular formula of Guanidine hydrochloride?

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Guanidine hydrochloride has CAS number 50-01-1 and molecular formula NH2C(=NH)NH2 · HCl. Full specifications appear in the table above and in the Certificate of Analysis.

What is the typical minimum order quantity and lead time for Guanidine hydrochloride?

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Sample quantities are available for technical evaluation; bulk MOQ depends on grade and packaging. In-stock material typically ships in 7–10 working days; custom-spec orders take 3–4 weeks. Tech Serve Solutions ships worldwide with full export documentation.

Do you provide a Certificate of Analysis (CoA) with each shipment?

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Yes. Every batch of Guanidine hydrochloride ships with a Certificate of Analysis covering assay, identity and purity tests, plus pharmacopoeia conformance where applicable. MSDS and TDS documents are available on request before order placement.

How should Guanidine hydrochloride be stored?

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Store Guanidine hydrochloride in its original sealed container in a cool, dry place away from direct sunlight and incompatible materials, in line with the storage guidance on the Safety Data Sheet. Reseal between dispensings.

What is Guanidine hydrochloride used for?

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Guanidine hydrochloride is used in biochemicals & reagents applications across pharmaceutical, research and industrial settings. Our technical team can advise on suitability for your specific process.

How do I request a quote for Guanidine hydrochloride?

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Request a quote with your required grade, quantity and destination via https://www.techservesolutions.in/contact or email info@techservesolutions.in. We respond with specifications, a Certificate of Analysis and pricing.

Need Guanidine hydrochloride in a specific grade or volume?

Request a quote