Fmoc-Ser(tBu)-ODhbt
Fmoc-Ser(tBu)-ODhbt (CAS: 109434-27-7), a protected amino acid derivative with the empirical formula C29H28N4O6 and a molecular weight of 528.56 g/mol. This compound is a critical building block in peptide synthesis, particularly for incorporating tert-butyl-protected serine residues. It is widely utilised in research laboratories and the pharmaceutical industry for the development of novel peptides and peptidomimetics.
- IUPAC
- Fmoc-O-tert-butyl-L-serine 3,4-dihydro-4-oxo-1,2,3-benzotriazin-3-ylester

Peptide Synthesis
Serves as a protected amino acid in solid-phase and solution-phase peptide synthesis. The Fmoc group allows for orthogonal deprotection strategies, while the tert-butyl group protects the serine side chain.
Medicinal Chemistry
Used in the construction of peptide-based drug candidates and peptidomimetics. Its specific structure facilitates the development of compounds with targeted biological activities.
Biochemical Research
Employed as a reagent in academic and industrial research for the synthesis of complex peptides and modified amino acids for biological studies.
| Molecular weight | 528.56 |
|---|---|
| Empirical formula | C29H28N4O6 |
| Storage temperature | −20°C |
| Impurities tested | ~10% solvents |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-Ser(tBu)-ODhbt primarily used for?
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Fmoc-Ser(tBu)-ODhbt is primarily used as a protected amino acid derivative in peptide synthesis, particularly for incorporating tert-butyl-protected serine residues into peptide chains.
What is the CAS number and empirical formula for Fmoc-Ser(tBu)-ODhbt?
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The CAS number for Fmoc-Ser(tBu)-ODhbt is 109434-27-7, and its empirical formula is C29H28N4O6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fmoc-Ser(tBu)-ODhbt with approximately 10% solvents. TSS does not represent this product as USP, BP, or EP grade.
What are the safety and handling recommendations for Fmoc-Ser(tBu)-ODhbt?
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Handling Fmoc-Ser(tBu)-ODhbt requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound has a WGK Germany rating of 3, indicating a high hazard level.
How is Fmoc-Ser(tBu)-ODhbt packed, shipped, and exported?
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Fmoc-Ser(tBu)-ODhbt is stored at -20°C and is available for global export by Tech Serve Solutions, a specialist supplier since 1998.
How can I request a sample or quote for Fmoc-Ser(tBu)-ODhbt?
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To request a sample or quote for Fmoc-Ser(tBu)-ODhbt, please contact Tech Serve Solutions directly through our website or sales department.
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