Fluphenazine dihydrochloride
Fluphenazine dihydrochloride (CAS: 146-56-5) is a trifluoromethylphenothiazine derivative with the molecular formula C22H26F3N3OS · 2HCl and a molecular weight of 510.44 g/mol. This compound functions primarily as a dopamine antagonist. It is a valuable research chemical used in studies related to cell signaling and neuroscience, particularly in understanding dopaminergic pathways and receptor interactions. Its specific properties make it a key reagent for biochemical and pharmacological investigations.
- IUPAC
- 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol dihydrochloride

Dopamine Receptor Antagonism Research
Fluphenazine dihydrochloride serves as a critical tool for investigating the function and modulation of dopamine receptors (DRD1, DRD2) in biological systems. It aids researchers in understanding dopaminergic neurotransmission and its role in neurological processes.
Cell Signaling Pathway Studies
This compound is utilized in cell biology to explore signal transduction pathways, particularly those influenced by dopaminergic and histaminergic signaling. It helps elucidate the mechanisms of cellular responses to neurotransmitter receptor activation.
Pharmacological Research Reagent
As a bioactive small molecule and an antagonist, Fluphenazine dihydrochloride is employed in preclinical research to model conditions related to dopaminergic system imbalances and to test potential therapeutic interventions.
| Molecular weight | 510.44 |
|---|---|
| Empirical formula | C22H26F3N3OS · 2HCl |


Hazard statements
- H301Toxic if swallowed
- H360May damage fertility or the unborn child
Precautionary statements
- P201Obtain special instructions before use
- P301IF SWALLOWED
- P308IF exposed or concerned
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812), DRD2(1813), HRH1(3269) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fluphenazine dihydrochloride used for?
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Fluphenazine dihydrochloride is primarily used in research settings for investigating dopamine receptor antagonism, cell signaling pathways, and as a tool in pharmacological studies related to neuroscience and biochemical processes.
What is the CAS number and formula for Fluphenazine dihydrochloride?
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The CAS number for Fluphenazine dihydrochloride is 146-56-5, and its empirical formula is C22H26F3N3OS · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Fluphenazine dihydrochloride as a research-grade chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. TSS does not represent this product as USP, BP, or EP grade unless explicitly stated in the specifications.
How should Fluphenazine dihydrochloride be handled and stored?
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Fluphenazine dihydrochloride is a Danger hazard with statements H301 (Toxic if swallowed) and H360 (May damage fertility or the unborn child). Handle with extreme caution in a well-ventilated area, using appropriate personal protective equipment. Store in a cool, dry place, away from incompatible materials. Always consult the Safety Data Sheet (SDS) before use.
Is Fluphenazine dihydrochloride a controlled substance?
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The provided data does not indicate that Fluphenazine dihydrochloride is a controlled substance. However, users should verify local regulations concerning its possession and use.
How are Fluphenazine dihydrochloride products packed and exported?
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Fluphenazine dihydrochloride is carefully packed according to international shipping regulations, including UN 2811 classification for toxic substances (6.1 / PGIII). TSS is experienced in exporting fine chemicals globally.
How can I request a sample or quote for Fluphenazine dihydrochloride?
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To request a sample or a quote for Fluphenazine dihydrochloride, please contact our sales team through the website or by phone, providing your specific requirements.
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