Flurbiprofen
Flurbiprofen (CAS: 5104-49-4), with the chemical formula C6H5C6H3(F)CH(CH3)CO2H and a molecular weight of 244.26 g/mol, is a nonsteroidal anti-inflammatory agent (NSAIA). It exhibits antipyretic, analgesic, and antifungal properties. Flurbiprofen is utilised in oral formulations for conditions such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, and topically in ophthalmic surgery to prevent miosis.
- IUPAC
- (±)-2-Fluoro-α-methyl-4-biphenylacetic acid,L-790,330
- Synonyms
- (±)-2-Fluoro-α-methyl-4-biphenylacetic acidL-790,330
Anti-inflammatory Agent
Flurbiprofen is an NSAIA used in oral formulations to manage symptoms of rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis. It helps reduce inflammation and pain associated with these conditions.
Ophthalmic Use
Topically, flurbiprofen is administered during ocular surgery to prevent or mitigate intraoperative miosis, the excessive constriction of the pupil.
Research and Study
This compound serves as a valuable tool in scientific research, including studies on the pathophysiological effects of NSAID enteropathy and the biotransformation by microbial species.
| Molecular weight | 244.26 |
|---|---|
| Linear formula | C6H5C6H3(F)CH(CH3)CO2H |
| Application | Flurbiprofen is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic, analgesic, and antifungal activity. Oral formulations of flurbiprofen may be used to treat rheumatoid arthritis, osteoarthritis and anklylosing spondylitis. Flurbiprofen is also used topically during ocular surgery to prevent or reduce intraoperative miosis. Flurbiprofen is structurally and pharmacologically related to ibuprofen. It is used to study the pathophysiological steps of NSAID enteropathy in the rat1 and the biotransformation of flurbiprofen by Cunninghamella species2. |
| Melting point | 110-112 °C(lit.) |
Hazard statements
- H301Toxic if swallowed
Precautionary statements
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T |
| Risk statements (R) | 25 |
| Safety statements (S) | 36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... ALB(213), APP(351), CYP1A2(1544), CYP2C9(1559)rat ... Ptgs1(24693) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Flurbiprofen primarily used for?
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Flurbiprofen is primarily used as a nonsteroidal anti-inflammatory agent (NSAIA) for treating inflammatory conditions like rheumatoid arthritis and osteoarthritis, and also topically in ophthalmic surgery.
What is the CAS number and chemical formula for Flurbiprofen?
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The CAS number for Flurbiprofen is 5104-49-4, and its chemical formula is C6H5C6H3(F)CH(CH3)CO2H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Flurbiprofen of a grade and purity suitable for research and laboratory use. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
What are the main safety concerns when handling Flurbiprofen?
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Flurbiprofen is classified with GHS06 symbol and 'Danger' signal word, with hazard statement H301 indicating it is toxic if swallowed. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and P2 respirator cartridges, is essential. Handle with extreme care according to safety guidelines.
How is Flurbiprofen packed, shipped, and exported?
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Flurbiprofen is carefully packed to ensure product integrity during transit and is available for domestic and international export by Tech Serve Solutions.
How can I request a sample or a quote for Flurbiprofen?
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To request a sample or a quote for Flurbiprofen, please contact our sales team through the website or your dedicated account manager.
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