2′-Deoxyuridine
2′-Deoxyuridine (CAS: 951-78-0), with the chemical formula C9H12N2O5 and a molecular weight of 228.20 g/mol, is a nucleoside analog. It serves as a foundational molecule for creating modified thymidine analogues. These derivatives are critical in research for studying DNA synthesis and degradation pathways. Tech Serve Solutions supplies this compound for laboratory and research applications.
- IUPAC
- 1-(2-Deoxy-β-D-ribofuranosyl)uracil,Uracil deoxyriboside
- Synonyms
- 1-(2-Deoxy-β-D-ribofuranosyl)uracilUracil deoxyriboside
Thymidine Analogue Synthesis
2′-Deoxyuridine is a precursor for synthesising various thymidine analogues, such as chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU), and iododeoxyuridine (IdU). These modified nucleosides are valuable tools for research.
DNA Synthesis Research
Derivatives of 2′-Deoxyuridine are used as labeling substrates to investigate mechanisms of DNA synthesis and degradation. This aids in understanding cellular processes and responses to various treatments.
Nucleoside Analog Studies
The compound and its analogues, like 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU), are employed in studies focusing on the behaviour and function of nucleosides within biological systems.
| Molecular weight | 228.20 |
|---|---|
| Empirical formula | C9H12N2O5 |
| Assay | 99-100% |
| Impurities tested | Thymidine, free |
| Application | 2′-Deoxyuridine (dU) is frequently halogenated to create thymidine analogues useful for studies of DNA synthesis and degradation mechanisms. Derivatized 2′-Deoxyuridines used as labeling substrates include chloro-2′-deoxyuridine (CldU), bromodeoxyuridine (BrdU) and/or iododeoxyuridine (IdU). Other useful analogues of 2′-deoxyuridine include 5-ethynyl-2′-deoxyuridine (DdU) and 5-hydroxymethyl-2′-deoxyuridine (HmdU). |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Slc29a1(63959) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Deoxyuridine used for?
+
2′-Deoxyuridine (CAS: 951-78-0) is primarily used as a precursor for synthesising thymidine analogues. These analogues are valuable in research for studying DNA synthesis and degradation mechanisms, and they are employed as labelling substrates in various biological studies.
What is the CAS number and formula for 2′-Deoxyuridine?
+
The CAS number for 2′-Deoxyuridine is 951-78-0, and its empirical formula (Hill notation) is C9H12N2O5.
What grade and purity does Tech Serve Solutions supply for 2′-Deoxyuridine?
+
Tech Serve Solutions supplies 2′-Deoxyuridine with an assay of 99-100%. This is a research-grade material; TSS does not represent it as USP, BP, EP, or other pharmacopoeial grades.
What are the safety and handling recommendations for 2′-Deoxyuridine?
+
2′-Deoxyuridine requires appropriate personal protective equipment, including eyeshields, gloves, and a type N95 (US) or type P1 (EN143) respirator filter. Users should consult the Safety Data Sheet for detailed handling and hazard information. It is classified under WGK Germany 3.
How is 2′-Deoxyuridine packed, shipped, and exported?
+
2′-Deoxyuridine is carefully packed according to industry standards to ensure safe transit and is available for global export. Specific packaging and shipping details are confirmed upon order.
How can I request a sample or quote for 2′-Deoxyuridine?
+
To request a sample or a quote for 2′-Deoxyuridine, please contact our sales team via the website or direct email. Please provide your specific requirements and shipping details.
▶ Related products
![(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (C8H13N3O4) — chemical structure, CAS 138472-01-2; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F138472-01-2.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide
C8H13N3O4
Biochemicals & Reagents![(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide (C14H18N4O4) — chemical structure, CAS 162626-99-5; Biochemicals & Reagents, fine chemical supplied by Tech Serve Solutions](/_next/image?url=https%3A%2F%2Fpub-f4d920c906024441a773a96f7098e551.r2.dev%2Fimages%2Fproducts%2F162626-99-5.png&w=3840&q=75)
(±)-(E)-4-Ethyl-2-[(Z)-hydroxyimino]-5-nitro-3-hexen-1-yl-nicotinamide
C14H18N4O4
Biochemicals & Reagents
(±)-2,5-Dimethoxy-4-bromoamphetamine hydrobromide
Biochemicals & Reagents
(±)-2-(p-Methoxyphenoxy)propionic acid
C10H12O4
Biochemicals & Reagents
(±)-2-Amino-6,7-dihydroxy-1,2,3,4-tetrahydronaphthalene hydrobromide
C10H13NO2·HBr
Biochemicals & Reagents
(±)-2-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxydecanoic acid
C10H20O3
Biochemicals & Reagents
(±)-3-Hydroxyoctanoic acid
C8H16O3
Biochemicals & Reagents▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis