2′-Deoxyinosine
2′-Deoxyinosine (CAS: 890-38-0), a nucleoside consisting of hypoxanthine and 2′-deoxyribose, is a key compound in biochemical research. It can arise from the deamination of adenosine within DNA. This compound serves as a valuable model for studying DNA adduct formation and radical chemistry that can impact DNA integrity. It is also instrumental in synthesising specialised fluorescent DNA probes for hybridisation studies.
- IUPAC
- 9-(2-Deoxy-β-D-ribofuranosyl)hypoxanthine
DNA Adduct and Radical Chemistry Studies
2′-Deoxyinosine is utilised as a model compound to investigate the mechanisms of adduct formation and radical-induced damage within DNA structures.
Fluorescent DNA Probe Synthesis
This nucleoside is employed in the production of advanced fluorescent DNA probes possessing self-avoidance capabilities, useful in hybridisation assays.
Biochemical Research
As a modified nucleoside, 2′-deoxyinosine finds applications in various fundamental biochemical and molecular biology research endeavours.
| Molecular weight | 252.23 |
|---|---|
| Empirical formula | C10H12N4O4 |
| Assay | ≥98% |
| Storage temperature | −20°C |
| Impurities tested | inosine, essentially free |
| Application | 2′-Deoxyinosine is a nucleoside composed of hypoxanthine attached to 2′-deoxyribose via a β-N9-glycosidic bond. 2′-Deoxyinosine in DNA can arise from deamination of adenosine. 2′-deoxyinsine can be used as a model compound to study the chemistry of adduct formation and radical chemistry that may affect DNA structures. 2′-Deoxyinosine is used to produce hybridization-sensitive fluorescent DNA probes with self-avoidance ability. |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-Deoxyinosine used for?
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2′-Deoxyinosine is used as a model compound to study DNA adduct formation and radical chemistry, and to produce hybridization-sensitive fluorescent DNA probes.
What is the CAS number and formula for 2′-Deoxyinosine?
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The CAS number for 2′-Deoxyinosine is 890-38-0 and its empirical formula is C10H12N4O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-Deoxyinosine with a purity of ≥98%. This product is intended for research and laboratory use and is not supplied as USP, BP, EP, or pharmacopoeia grade.
How should 2′-Deoxyinosine be handled and stored?
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Handle 2′-Deoxyinosine with appropriate personal protective equipment, including eyeshields and gloves. It should be stored at −20°C. Refer to the safety data sheet for full handling information. The WGK Germany classification is 3.
How is 2′-Deoxyinosine packed, shipped, and exported?
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Tech Serve Solutions is a global supplier and exporter of fine chemicals, ensuring secure and compliant packaging for international shipment.
How can I request a sample or quote for 2′-Deoxyinosine?
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Please contact our sales team through the website or by phone to request a sample or a detailed quotation.
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