2′-O-Methyladenosine
2′-O-Methyladenosine (CAS: 2140-79-6) is a modified nucleoside with the molecular formula C11H15N5O4 and a molecular weight of 281.27 g/mol. This compound serves as a valuable building block in biochemical research, particularly in the synthesis of modified oligonucleotides. Its structure allows for specific incorporation into nucleic acid sequences, enabling the study of their function and properties in various biological contexts.

Oligonucleotide Synthesis
2′-O-Methyladenosine is used as a modified phosphoramidite or nucleoside building block for the synthesis of custom oligonucleotides. These modified sequences are crucial for research in areas like gene silencing and diagnostics.
Biochemical Research
As a nucleoside analog, it is employed in fundamental biochemical studies to investigate enzyme mechanisms, nucleic acid structure-activity relationships, and the development of novel therapeutic agents.
Molecular Biology Applications
This compound can be incorporated into RNA or DNA strands to study the effects of 2'-O-methylation on nucleic acid stability, hybridization properties, and interactions with proteins.
| Molecular weight | 281.27 |
|---|---|
| Empirical formula | C11H15N5O4 |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 2′-O-Methyladenosine used for?
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2′-O-Methyladenosine is used in biochemical research, particularly for the synthesis of modified oligonucleotides, and for studying nucleic acid structure and function.
What is the CAS number and chemical formula for 2′-O-Methyladenosine?
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The CAS number is 2140-79-6 and the chemical formula is C11H15N5O4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 2′-O-Methyladenosine typically as a research-grade chemical. The exact assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should 2′-O-Methyladenosine be handled and stored?
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Handle 2′-O-Methyladenosine with appropriate personal protective equipment, including eyeshields and gloves. A P1 (EN143) or N95 (US) respirator filter is recommended. Store at −20°C.
Is 2′-O-Methyladenosine a controlled substance?
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The provided data does not indicate that 2′-O-Methyladenosine (CAS: 2140-79-6) is a controlled substance.
How is 2′-O-Methyladenosine packed and shipped?
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Tech Serve Solutions securely packs and exports chemicals globally, adhering to all relevant shipping regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a sample or quote for 2′-O-Methyladenosine?
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To request a sample or a quote for 2′-O-Methyladenosine, please contact our sales team via the website or email, providing your contact details and the required quantity.
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