Fmoc-(S)-3-amino-4-(4-chloro-phenyl)-butyric acid
Fmoc-(S)-3-amino-4-(4-chloro-phenyl)-butyric acid (CAS 270596-43-5) is a protected amino acid derivative with the empirical formula C25H22ClNO4 and a molecular weight of 435.90 g/mol. This compound serves as a valuable building block in organic synthesis, particularly in the development of novel pharmaceuticals and peptidomimetics. Its structure incorporates the Fmoc protecting group for controlled peptide chain elongation, alongside a chlorophenyl moiety, making it suitable for applications requiring specific steric and electronic properties.
- IUPAC
- (S)-Fmoc-4-chloro-β-Homophe-OH,(S)-3-(Fmoc-amino)-4-(4-chlorophenyl)butyric acid,(S)-4-(4-Chlorophenyl)-3-(Fmoc-amino)butyric acid,Fmoc-4-chloro-L-β-homophenylalanine
- Synonyms
- (S)-Fmoc-4-chloro-β-Homophe-OH(S)-3-(Fmoc-amino)-4-(4-chlorophenyl)butyric acid(S)-4-(4-Chlorophenyl)-3-(Fmoc-amino)butyric acidFmoc-4-chloro-L-β-homophenylalanine

Peptide Synthesis
Utilised as a protected amino acid in solid-phase and solution-phase peptide synthesis, enabling the incorporation of a non-proteinogenic amino acid residue into peptide sequences.
Medicinal Chemistry
Serves as a key intermediate in the synthesis of drug candidates, particularly where modified amino acid structures are required to enhance pharmacokinetic or pharmacodynamic properties.
Organic Synthesis Building Block
A versatile chiral building block employed in the construction of complex organic molecules and novel chemical entities for research purposes.
| Molecular weight | 435.90 |
|---|---|
| Empirical formula | C25H22ClNO4 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-(S)-3-amino-4-(4-chloro-phenyl)-butyric acid used for?
+
This compound is primarily used as a building block in organic synthesis, particularly in peptide synthesis and medicinal chemistry for the development of novel pharmaceutical agents and peptidomimetics.
What are the CAS number and molecular formula for Fmoc-(S)-3-amino-4-(4-chloro-phenyl)-butyric acid?
+
The CAS number is 270596-43-5 and the empirical formula (Hill notation) is C25H22ClNO4.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies this product as a research chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or any other pharmacopoeial grade.
How is Fmoc-(S)-3-amino-4-(4-chloro-phenyl)-butyric acid supplied and shipped?
+
This chemical is carefully packed and exported by Tech Serve Solutions, adhering to all relevant shipping regulations for fine chemicals.
What safety precautions should be taken when handling this compound?
+
Users should consult the Safety Data Sheet (SDS) for specific handling, storage, and disposal information. Appropriate personal protective equipment (PPE) should be worn.
How can I request a sample or quote for this product?
+
To request a sample or a quote, please contact our sales team through the provided contact details on the Tech Serve Solutions website, specifying the product name and CAS number.
▶ Related products

1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis

1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more

3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis

3-Methyl-1,5-pentanediol
Chemical Synthesis

3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis