(5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid
(5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid (CAS 857303-87-8), with a molecular weight of 347.24 g/mol, is a chiral organocatalyst. This compound plays a crucial role in asymmetric synthesis, particularly noted for its application in the enantioselective alpha-fluorination of aldehydes. Supplied by Tech Serve Solutions, it is available at a purity of 97%.
- IUPAC
- (5R)-2,2,3-Trimethyl-5-phenylmethyl-4-imidazolidinone dichloroacetic acid
- Synonyms
- 857303-87-8, C15H20Cl2N2O3, (5R)-2,2,3-Trimethyl-5-phenylmethyl-4-imidazolidinone dichloroacetic acid
Enantioselective α-Fluorination of Aldehydes
This imidazolidinone derivative has been successfully employed in the first reported organocatalytic method for the enantioselective alpha-fluorination of aldehydes. It facilitates the stereoselective introduction of fluorine atoms into organic molecules.
Asymmetric Synthesis
As a chiral catalyst, (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid is instrumental in asymmetric synthesis, enabling the preparation of enantiomerically enriched compounds essential for pharmaceutical and fine chemical development.
MacMillan Imidazolidinone Organocatalysis
This compound belongs to the class of MacMillan imidazolidinone organocatalysts, which are widely recognised for their utility in promoting a variety of stereoselective transformations in organic chemistry.
| Molecular weight | 347.24 |
|---|---|
| Empirical formula | C15H20Cl2N2O3 |
| Assay | 97% |
| Application | Utilized in the first example of organocatalytic enantioselective α-fluorination of aldehydes.1 |
| Melting point | 122-126 °C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid used for?
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It is primarily used in asymmetric synthesis, notably for the enantioselective alpha-fluorination of aldehydes, and falls under the category of MacMillan Imidazolidinone OrganoCatalysts.
What is the CAS number and molecular formula for this compound?
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The CAS number is 857303-87-8 and the empirical formula is C15H20Cl2N2O3.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this chemical with an assay of 97%. It is not represented as USP, BP, EP, or any pharmacopoeia grade.
What are the safety and handling requirements for this chemical?
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Handling requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. The compound is classified under WGK 2 in Germany.
How are your products packed and shipped?
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Tech Serve Solutions exports fine chemicals globally, ensuring appropriate packaging for safe transport and handling according to international regulations.
How can I request a sample or quote for this chemical?
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Please contact our sales team through the website or by phone to request a sample or a quotation for (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone dichloroacetic acid.
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