(5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone monohydrochloride
(5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone monohydrochloride (CAS: 323196-43-6) is a chiral organocatalyst supplied by Tech Serve Solutions. With a molecular weight of 254.76 g/mol, this compound is primarily utilised in advanced asymmetric synthesis. It has been instrumental in developing highly enantioselective reactions, including Diels-Alder and 1,3-dipolar additions, making it a valuable reagent for creating complex chiral molecules in research and development.
- IUPAC
- (5R)-2,2,3-Trimethyl-5-phenylmethyl-4-imidazolidinone monohydrochloride
- Synonyms
- 323196-43-6C13H19ClN2O(5R)-2,2,3-Trimethyl-5-phenylmethyl-4-imidazolidinone monohydrochloride
Enantioselective Organocatalytic Diels-Alder Reactions
This imidazolidinone derivative is a key catalyst in the first reported highly enantioselective organocatalytic Diels-Alder reactions. It enables the controlled formation of chiral cyclic products with high stereoselectivity.
1,3-Dipolar Addition Reactions
The compound serves as an effective catalyst for asymmetric 1,3-dipolar addition reactions. These reactions are crucial for constructing diverse heterocyclic scaffolds with precise control over stereochemistry.
Chiral Synthesis
As a chiral catalyst and reagent, it plays a significant role in asymmetric synthesis, facilitating the production of enantiomerically enriched compounds essential for pharmaceuticals and fine chemicals.
| Molecular weight | 254.76 |
|---|---|
| Empirical formula | C13H19ClN2O |
| Assay | 97% |
| Optical activity | [α]20/D +67°, c = 1 in H2O |
| Application | Used in first highly enantioselective organocatalytic Diels-Alder reaction1 and 1,3-dipolar addition.2 |
| Melting point | 157-161 °C |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone monohydrochloride used for?
+
(5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone monohydrochloride is primarily used as a chiral organocatalyst in asymmetric synthesis, notably in enantioselective Diels-Alder and 1,3-dipolar addition reactions.
What is the CAS number and chemical formula?
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The CAS number is 323196-43-6, and the empirical formula is C13H19ClN2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. We do not represent this product as USP, BP, EP, or any pharmacopoeia grade.
How should this chemical be handled safely?
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This compound is classified as a Warning hazard. It may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, in a well-ventilated area. Avoid breathing dust.
Is this product available for export?
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Yes, Tech Serve Solutions is a global supplier and exporter of fine chemicals and laboratory reagents.
How can I request a sample or quote?
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Please contact our sales team via the website to request a sample or obtain a quotation for (5R)-(+)-2,2,3-Trimethyl-5-benzyl-4-imidazolidinone monohydrochloride.
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