N-Boc-2-indolyldimethylsilanol
N-Boc-2-indolyldimethylsilanol (CAS 784161-48-4) is a heterocyclic building block with a molecular weight of 291.42 g/mol. This compound serves as a valuable silicon nucleophile, primarily utilised in palladium-catalyzed cross-coupling reactions within advanced chemical synthesis. Its structure incorporates an indole core and a protected silanol group, making it suitable for constructing complex organic molecules. It is supplied by TSS with a minimum purity of 95%.
- IUPAC
- 2-(hydroxydimethylsilyl)-1,1-dimethylethylindole-1-carboxylic acid ester,N-Boc-indol-2-yldimethylsilanol
Palladium-Catalyzed Cross-Coupling
This silanol is a key silicon nucleophile enabling palladium-catalyzed cross-coupling reactions. It is employed to introduce the indolyl moiety into various organic structures under specific catalytic conditions.
Heterocyclic Synthesis
As a functionalised indole derivative, it is a useful building block for synthesising more complex heterocyclic compounds. Its reactive silanol group allows for further chemical transformations.
Organic Synthesis Reagent
Utilised in general organic synthesis, this compound facilitates the construction of carbon-carbon and carbon-heteroatom bonds. It is part of a broader range of specialised reagents for fine chemical production.
| Molecular weight | 291.42 |
|---|---|
| Linear formula | ((C8H5N)(CO2C(CH3)3))Si(CH3)2(OH) |
| Assay | 95% |
| Refractive index | n20/D 1.545 |
| Storage temperature | 2-8°C |
| Application | A useful silicon nucleophile for Pd-catalyzed cross-coupling.4 |
| Flash point | >110 °C / >230 °F |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-2-indolyldimethylsilanol used for?
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N-Boc-2-indolyldimethylsilanol is used as a silicon nucleophile in palladium-catalyzed cross-coupling reactions and as a heterocyclic building block in organic synthesis.
What is the CAS number and chemical formula for N-Boc-2-indolyldimethylsilanol?
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The CAS number is 784161-48-4. The linear formula is ((C8H5N)(CO2C(CH3)3))Si(CH3)2(OH).
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-2-indolyldimethylsilanol with a minimum purity of 95%. This is a research grade material and not intended for USP, EP, or BP use.
What are the safety and handling considerations for N-Boc-2-indolyldimethylsilanol?
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N-Boc-2-indolyldimethylsilanol has a flash point above 110°C (230°F) and a WGK rating of 3 in Germany, indicating it is hazardous to water. Appropriate personal protective equipment should be worn, and it should be handled in a well-ventilated area. Refer to the Safety Data Sheet for detailed handling procedures.
How is N-Boc-2-indolyldimethylsilanol packed and shipped?
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N-Boc-2-indolyldimethylsilanol is typically packed in appropriate containers to maintain its integrity during transport. TSS exports globally, adhering to all relevant shipping regulations for chemical substances.
How can I request a sample or quote for N-Boc-2-indolyldimethylsilanol?
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To request a sample or a quotation for N-Boc-2-indolyldimethylsilanol, please contact the TSS sales department via our website or by calling our customer service line.
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