N-Boc-2-aminomethylpyridine
N-Boc-2-aminomethylpyridine (CAS: 134807-28-6), a pyridine derivative with the molecular formula C11H16N2O2 and a molecular weight of 208.26 g/mol, serves as a valuable building block in chemical synthesis. Its structure, featuring a protected aminomethyl group on a pyridine ring, makes it useful in the development of complex organic molecules. This compound is primarily utilised in research and development settings for the creation of novel chemical entities.
- IUPAC
- N-(tert-Butoxycarbonyl)-2-aminomethylpyridine
- Synonyms
- N-(tert-Butoxycarbonyl)-2-aminomethylpyridine

Organic Synthesis Intermediate
N-Boc-2-aminomethylpyridine is employed as a key intermediate in multi-step organic syntheses. The tert-butoxycarbonyl (Boc) protecting group allows for selective reactions at other sites before its controlled removal.
Pharmaceutical Research
This compound can be incorporated into synthetic routes targeting potential pharmaceutical agents, particularly those involving pyridine scaffolds. Its use facilitates the construction of molecules with diverse pharmacological properties.
Heterocyclic Chemistry
As a functionalised pyridine derivative, it is a useful reagent in heterocyclic chemistry research. It enables the introduction of the 2-aminomethylpyridine moiety into larger molecular structures.
| Molecular weight | 208.26 |
|---|---|
| Empirical formula | C11H16N2O2 |
| Assay | 97% |
| Density | 1.0699 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.5020(lit.) |

Hazard statements
- H302Harmful if swallowed
- H315Causes skin irritation
- H317May cause an allergic skin reaction
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | >110 °C / >230 °F |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-36/37/38-43 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is N-Boc-2-aminomethylpyridine used for?
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N-Boc-2-aminomethylpyridine is primarily used as a building block in organic synthesis, particularly in pharmaceutical research and heterocyclic chemistry for constructing complex molecules.
What are the CAS number and formula for N-Boc-2-aminomethylpyridine?
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The CAS number is 134807-28-6, and the empirical formula is C11H16N2O2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies N-Boc-2-aminomethylpyridine with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety considerations when handling N-Boc-2-aminomethylpyridine?
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This compound is classified as harmful if swallowed, causes skin irritation, may cause an allergic skin reaction, causes serious eye irritation, and may cause respiratory irritation (H302-H315-H317-H319-H335). Appropriate personal protective equipment, including gloves, eyeshields, and a respirator, should be used.
How is N-Boc-2-aminomethylpyridine packed and shipped?
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Tech Serve Solutions ensures appropriate packaging for export, adhering to international shipping regulations for chemical substances.
How can I request a sample or quote for N-Boc-2-aminomethylpyridine?
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Please contact our sales team via the website or email to request a sample or a quotation for N-Boc-2-aminomethylpyridine.
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