4-Ethoxyaniline
4-Ethoxyaniline (CAS: 156-43-4), a derivative of aniline with the chemical formula C2H5OC6H4NH2, is a valuable organic intermediate. With a molecular weight of 137.18 g/mol, this compound serves as a critical building block in the synthesis of various organic molecules. Its properties make it suitable for applications in chemical research and development, particularly within the pharmaceutical and dye industries, contributing to the creation of complex chemical structures.
- IUPAC
- 4-Ethoxyaniline,p-Phenetidine
- Synonyms
- p-Phenetidine

Organic Synthesis Intermediate
4-Ethoxyaniline is widely employed as a precursor in the synthesis of more complex organic compounds. Its amine and ethoxy functionalities allow for diverse chemical transformations, making it a versatile component in multi-step synthetic routes.
Pharmaceutical Intermediates
This compound is utilised in the development of pharmaceutical agents. It can be incorporated into the structures of active pharmaceutical ingredients (APIs) or used in the synthesis of key intermediates, contributing to drug discovery and manufacturing.
Dye and Pigment Production
4-Ethoxyaniline finds application in the manufacturing of dyes and pigments. Its structure can be modified to create chromophores, contributing to the vibrant colours used across various industries.
Research and Development
As a fundamental organic building block, 4-Ethoxyaniline is frequently used in academic and industrial research settings. It supports the exploration of novel chemical reactions and the development of new materials.
| Molecular weight | 137.18 |
|---|---|
| Linear formula | C2H5OC6H4NH2 |
| Assay | 98% |
| Boiling point | 250 °C(lit.) |
| Density | 1.065 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.559(lit.) |
| Melting point | 2-5 °C(lit.) |


Hazard statements
- H302Harmful if swallowed
- H311Toxic in contact with skin
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H334May cause allergy or asthma symptoms if inhaled
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P342
| Protective equipment | Eyeshields, Faceshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 140 °C / 284 °F |
| Transport (UN / ADR) | UN 2311 6.1 / PGIII |
| Water hazard class (WGK, DE) | 1 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22-36-43-68 |
| Safety statements (S) | 36/37-46 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethoxyaniline used for?
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4-Ethoxyaniline is primarily used as an intermediate in organic synthesis, particularly in the production of pharmaceuticals, dyes, and pigments, as well as in chemical research and development.
What are the CAS number and chemical formula for 4-Ethoxyaniline?
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The CAS number for 4-Ethoxyaniline is 156-43-4, and its chemical formula is C2H5OC6H4NH2.
What grade and purity does Tech Serve Solutions supply for 4-Ethoxyaniline?
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Tech Serve Solutions supplies 4-Ethoxyaniline with an assay of 98%. This product is supplied for technical and research purposes and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should 4-Ethoxyaniline be handled safely?
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4-Ethoxyaniline is a hazardous substance. It is harmful if swallowed, toxic in contact with skin, causes serious eye irritation, and harmful if inhaled. Appropriate personal protective equipment, including eyeshields, faceshields, gloves, and respiratory protection (e.g., a full-face respirator or a type ABEK filter), should be used. Handle in a well-ventilated area and avoid breathing dust/fume/gas/mist/vapours/spray.
How is 4-Ethoxyaniline packed, shipped, and exported?
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4-Ethoxyaniline is packed and shipped in compliance with international regulations for hazardous materials. Tech Serve Solutions, as a global supplier and exporter, ensures that all shipments meet the necessary safety and transport standards.
How can I request a sample or quote for 4-Ethoxyaniline?
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To request a sample or a quote for 4-Ethoxyaniline, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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