4-Ethoxybenzoyl chloride
4-Ethoxybenzoyl chloride (CAS: 16331-46-7), with the linear formula C2H5OC6H4COCl and a molecular weight of 184.62 g/mol, is a reactive acyl halide. It serves as a valuable intermediate and building block in organic synthesis, particularly for introducing the 4-ethoxybenzoyl moiety into various chemical structures. This compound is primarily utilised in research and development settings for the creation of novel materials and molecules.

Organic Synthesis Intermediate
4-Ethoxybenzoyl chloride is employed as a key intermediate in the synthesis of more complex organic molecules. Its reactive acyl chloride group facilitates esterification, amidation, and other acylation reactions.
Building Block for Specialty Chemicals
This compound acts as a fundamental building block for the development of specialty chemicals, pharmaceuticals, and advanced materials. It enables the incorporation of the 4-ethoxybenzoyl functional group into target compounds.
Research and Development
Utilised in chemical synthesis studies, 4-Ethoxybenzoyl chloride aids researchers in exploring new reaction pathways and developing novel chemical entities.
| Molecular weight | 184.62 |
|---|---|
| Linear formula | C2H5OC6H4COCl |
| Assay | 98% |
| Boiling point | 142-145 °C/20 mmHg(lit.) |
| Refractive index | n20/D 1.567(lit.) |
| Application | 4-Ethoxybenzoyl chloride may be used in chemical synthesis studies. |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Transport (UN / ADR) | UN 3265 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is 4-Ethoxybenzoyl chloride used for?
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4-Ethoxybenzoyl chloride is used as an intermediate and building block in organic synthesis, particularly for introducing the 4-ethoxybenzoyl group into various chemical structures in research and development.
What are the CAS number and formula for 4-Ethoxybenzoyl chloride?
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The CAS number is 16331-46-7 and the linear formula is C2H5OC6H4COCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies 4-Ethoxybenzoyl chloride with an assay of 98%. This product is intended for research and technical use and is not supplied as USP, BP, EP, or pharmaceutical grade.
How should 4-Ethoxybenzoyl chloride be handled safely?
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4-Ethoxybenzoyl chloride is classified as corrosive and may cause respiratory irritation. Handling requires appropriate personal protective equipment, including gloves, goggles, face shields, and respiratory protection, in a well-ventilated area. Refer to the Safety Data Sheet for detailed information.
Is 4-Ethoxybenzoyl chloride a controlled substance?
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The provided data does not indicate that 4-Ethoxybenzoyl chloride is a controlled substance.
How is 4-Ethoxybenzoyl chloride packed and shipped?
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Tech Serve Solutions exports chemicals globally, adhering to all relevant shipping and handling regulations for hazardous materials. Specific packaging details are available upon request.
How can I request a quote or sample for 4-Ethoxybenzoyl chloride?
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To request a quote or a sample of 4-Ethoxybenzoyl chloride, please contact our sales team via the website or direct email, providing your contact details and the quantity required.
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