Fmoc-(S)-3-amino-4-(2-trifluoromethyl-phenyl)-butyric acid
Fmoc-(S)-3-amino-4-(2-trifluoromethyl-phenyl)-butyric acid (CAS: 270065-75-3) is a chiral building block with the molecular formula C26H22F3NO4 and a molecular weight of 469.45 g/mol. This compound is valuable in organic synthesis, particularly for the construction of complex molecules. Its structure, featuring a trifluoromethyl-substituted phenyl ring and an Fmoc-protected amine, makes it a useful intermediate in the development of novel pharmaceuticals and other fine chemicals.
- IUPAC
- (S)-3-(Fmoc-amino)-4-[2-(trifluoromethyl)phenyl]butyric acid,(S)-Fmoc-2-(trifluoromethyl)-β-Homophe-OH,Fmoc-2-(trifluoromethyl)-L-β-homophenylalanine
- Synonyms
- (S)-3-(Fmoc-amino)-4-[2-(trifluoromethyl)phenyl]butyric acid(S)-Fmoc-2-(trifluoromethyl)-β-Homophe-OHFmoc-2-(trifluoromethyl)-L-β-homophenylalanine

Peptide Synthesis
Serves as a non-canonical amino acid building block in solid-phase peptide synthesis (SPPS) for creating modified peptides with altered pharmacological properties.
Organic Synthesis
A versatile intermediate for constructing complex organic molecules, particularly those incorporating trifluoromethylphenyl moieties and chiral centers.
Medicinal Chemistry
Used in the research and development of new drug candidates, leveraging its unique structural features for molecular design.
Chemical Research
Employed as a reagent in academic and industrial laboratories exploring novel synthetic routes and chemical entities.
| Molecular weight | 469.45 |
|---|---|
| Empirical formula | C26H22F3NO4 |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Fmoc-(S)-3-amino-4-(2-trifluoromethyl-phenyl)-butyric acid used for?
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This compound is primarily used as a chiral building block in organic synthesis, particularly in peptide synthesis and medicinal chemistry for the development of novel molecules.
What is the CAS number and formula?
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The CAS number is 270065-75-3 and the empirical formula is C26H22F3NO4.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product for research and chemical synthesis purposes. The specific grade and purity are available upon request, and it is not represented as USP, BP, EP, or any other pharmacopoeia grade.
How should Fmoc-(S)-3-amino-4-(2-trifluoromethyl-phenyl)-butyric acid be handled?
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Refer to the Safety Data Sheet (SDS) for detailed hazard information and handling procedures. General precautions for handling fine chemicals should be observed.
Can this chemical be exported globally?
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Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including this product, adhering to all relevant export regulations.
How can I request a quote or sample?
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Please contact our sales team through the website or by phone to request a quote or sample of Fmoc-(S)-3-amino-4-(2-trifluoromethyl-phenyl)-butyric acid.
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