Ethylenediaminetetraacetic acid tetrasodium salt hydrate
Ethylenediaminetetraacetic acid tetrasodium salt hydrate (CAS: 194491-31-1) is a chelating agent with the linear formula (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O. It is an inhibitor of metalloproteases by chelating essential metal ions. Commonly used in solutions to prevent enzyme activity, this compound is a key reagent in chemical synthesis and various laboratory applications requiring metal ion control. Supplied with a minimum 98% assay.
- IUPAC
- Tetrasodium ethylenediaminetetraacetate hydrate
Metalloprotease Inhibition
EDTA acts as a potent inhibitor of metalloproteases by chelating the zinc ion crucial for their active site. It is effective in concentrations of 1-10 mM, preventing unwanted enzymatic degradation in biological and chemical systems.
Anticoagulation
The tetrasodium salt of EDTA is frequently used as an anticoagulant in blood collection tubes. It effectively binds calcium ions, preventing blood clotting and preserving blood samples for analysis.
Chemical Synthesis
Utilised as a synthetic reagent, this compound plays a role in processes where precise control over metal ion concentrations is required. Its chelating ability is fundamental in various organic and inorganic syntheses.
EDTA Derivatives
As an EDTA derivative, it is a versatile compound employed in applications that leverage the strong binding affinity of EDTA for metal ions. This includes use in detergents, cosmetics, and analytical chemistry.
| Molecular weight | 380.17 (anhydrous basis) |
|---|---|
| Linear formula | (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O |
| Assay | 98% |
| Application | EDTA is an inhibitor of metalloproteases, at effective concentrations of 1-10 mM. EDTA acts as a chelator of the zinc ion in the active site of metalloproteases, and can also inhibit other metal ion-dependent proteases such as calcium-dependent cysteine proteases. For use as an anticoagulant, disodium or tripotassium salts of EDTA are most commonly used. The optimal concentration is 1.5 mg per ml of blood. |
| Melting point | >300 °C(lit.) |
Hazard statements
- H302Harmful if swallowed
- H318Causes serious eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22-41 |
| Safety statements (S) | 26-39-46 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethylenediaminetetraacetic acid tetrasodium salt hydrate used for?
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It is used as a metalloprotease inhibitor, anticoagulant, and a versatile reagent in chemical synthesis and laboratory applications requiring metal ion control.
What is the CAS number and formula for Ethylenediaminetetraacetic acid tetrasodium salt hydrate?
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The CAS number is 194491-31-1 and the linear formula is (NaOOCCH2)2NCH2CH2N(CH2COONa)2 · xH2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethylenediaminetetraacetic acid tetrasodium salt hydrate with a minimum assay of 98%. We do not represent this product as USP, BP, or EP grade unless explicitly stated.
How should Ethylenediaminetetraacetic acid tetrasodium salt hydrate be handled?
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Handle with appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. It is classified as causing serious eye damage and is harmful if swallowed.
How is Ethylenediaminetetraacetic acid tetrasodium salt hydrate packed and shipped?
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Products are carefully packed and exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for chemical substances.
How can I request a quote or sample?
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Please use the 'Request a Quote' or 'Request a Sample' button on our website, or contact our sales team directly with your specific requirements.
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