Ethylenediaminetetraacetic acid disodium salt dihydrate
Ethylenediaminetetraacetic acid disodium salt dihydrate (CAS: 6381-92-6), with the molecular formula C10H14N2Na2O8 · 2H2O and a molecular weight of 372.24, is a chelating agent. It effectively binds divalent cations, thereby inhibiting metalloenzymes like carboxypeptidases and collagenases that require these ions for activity. This compound is widely utilised in biochemical research and industrial applications requiring metal ion control.
- IUPAC
- Disodium ethylenediaminetetraacetate dihydrate,EDTA disodium salt,EDTA-Na2,Edathamil,Edetate disodium salt dihydrate,Sequestrene Na2
- Synonyms
- Disodium ethylenediaminetetraacetate dihydrateEDTA disodium saltEDTA-Na2EdathamilEdetate disodium salt dihydrateSequestrene Na2
Enzyme Inhibition
Acts as a potent inhibitor for metalloproteases and other enzymes that rely on divalent metal cations for their catalytic function, such as carboxypeptidase A and B, and collagenase. It functions by chelating the essential metal cofactor.
Chelation and Metal Ion Sequestration
This compound serves as an effective chelator, binding strongly to various divalent and trivalent metal ions. This property is crucial in applications where controlling free metal ion concentration is necessary for process stability or product integrity.
Biochemical Research Reagent
Utilised as a versatile reagent in biochemical and molecular biology laboratories for a range of applications, including preventing metal-dependent degradation of proteins and controlling ion concentrations in experimental buffers.
Industrial Applications
Finds use in industrial processes where metal ion control is required, such as in chemical synthesis or in formulations to prevent metal-catalysed degradation or precipitation.
| Molecular weight | 372.24 |
|---|---|
| Empirical formula | C10H14N2Na2O8 · 2H2O |
| Assay | 97% |
| Grade | JIS special grade |
| Solubility | H2O: soluble, clear, colorless |
| Impurities tested | ≤0.005% Insolubles≤0.1% Nitrilotriacetic acid (NTA) |
| Application | Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity. |
| Melting point | 248 °C (dec.)(lit.) |
| Suitability | meets USP testing specifications |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Flash point | >100 °C / >212 °F |
| Water hazard class (WGK, DE) | 2 |
| Cation traces | Fe: ≤0.005%Pb: ≤0.002% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Availability | available only in Japan |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethylenediaminetetraacetic acid disodium salt dihydrate used for?
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It is primarily used as a chelating agent to bind divalent cations, thereby inhibiting enzymes such as metalloproteases (e.g., carboxypeptidase A, carboxypeptidase B, collagenase) that require these metal ions for activity. It is also used as a biochemical reagent.
What are the CAS number and chemical formula for Ethylenediaminetetraacetic acid disodium salt dihydrate?
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The CAS number is 6381-92-6, and the chemical formula is C10H14N2Na2O8 · 2H2O.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies this product with an assay of 97%. It meets USP testing specifications and is supplied as JIS special grade. TSS does not represent this product as USP, BP, or EP grade.
What safety precautions should be taken when handling this chemical?
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When handling, ensure adequate personal protective equipment is worn, including eyeshields and gloves. Use a type N95 (US) or type P1 (EN143) respirator filter if airborne exposure is possible. It is classified under WGK Germany 2.
Is Ethylenediaminetetraacetic acid disodium salt dihydrate available for export?
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This product is available only in Japan. Tech Serve Solutions specialises in global supply and export of fine chemicals, pharmaceutical intermediates, and laboratory reagents.
How can I request a quote or sample?
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Please contact Tech Serve Solutions directly through our website or sales channels to request a quote or inquire about sample availability for this product.
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