Ethyl dichlorophosphite
Ethyl dichlorophosphite (CAS 1498-42-6) is an organophosphorus compound with the linear formula C2H5OPCl2 and a molecular weight of 146.94 g/mol. This clear liquid, with a refractive index of n20/D 1.464, serves as a valuable reagent in organic synthesis. Its primary application lies in the construction of more complex molecules, particularly in the preparation of specific organic building blocks and phosphorus-containing compounds.
- IUPAC
- Ethyl phosphorodichloridite
Synthesis of Peptide Derivatives
Ethyl dichlorophosphite has been documented for its use in the synthesis of peptide derivatives. This highlights its utility in complex organic transformations relevant to medicinal chemistry and biochemical research.
Organic Building Block
As a reactive organophosphorus halide, it functions as a versatile building block in organic synthesis. It can be employed to introduce phosphorus moieties into various organic structures.
Reagent in Chemical Synthesis
This compound acts as a key intermediate and reagent in chemical synthesis, enabling the formation of new carbon-phosphorus or phosphorus-heteroatom bonds.
| Molecular weight | 146.94 |
|---|---|
| Linear formula | C2H5OPCl2 |
| Assay | 98% |
| Boiling point | 117-118 °C(lit.) |
| Density | 1.286 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.464(lit.) |
| Storage temperature | 2-8°C |
| Application | Ethyl dichlorophosphite was used in the synthesis of peptide derivatives1. |
Hazard statements
- H225Highly flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 4 °C / 39.2 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-34 |
| Safety statements (S) | 16-26-27-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl dichlorophosphite used for?
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Ethyl dichlorophosphite is primarily used as a building block in organic synthesis, including the preparation of peptide derivatives and other phosphorus-containing compounds.
What is the CAS number and formula for Ethyl dichlorophosphite?
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The CAS number for Ethyl dichlorophosphite is 1498-42-6, and its linear formula is C2H5OPCl2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl dichlorophosphite with an assay of 98%. TSS does not represent this product as USP, BP, EP, or pharmacopoeia grade.
How should Ethyl dichlorophosphite be handled safely?
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Ethyl dichlorophosphite is a flammable liquid and causes severe skin burns and eye damage (H225-H314). Handling requires full protective equipment, including a face shield, respirator, gloves, and goggles. Work should be conducted in a well-ventilated area away from ignition sources.
How is Ethyl dichlorophosphite shipped by Tech Serve Solutions?
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Ethyl dichlorophosphite is shipped as a UN 2924, Hazard Class 8(3), Packing Group II substance, complying with international transport regulations.
How can I request a quote or sample?
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To request a quote or sample of Ethyl dichlorophosphite, please contact the Tech Serve Solutions sales team through our website or by phone.
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