Ethyl difluoroacetate
Ethyl difluoroacetate (CAS 454-31-9), with the linear formula F₂CHCO₂C₂H₅ and a molecular weight of 124.09 g/mol, is a fluorinated organic building block. This ester is characterised by its difluoromethyl group, making it a valuable intermediate in organic synthesis. It is primarily utilised as a reagent in the development of novel chemical entities and advanced materials, contributing to the synthesis of complex molecules requiring precise fluorination.
Fluorinated Intermediate
Ethyl difluoroacetate serves as a key building block in the synthesis of organofluorine compounds. Its difluoromethyl group can be incorporated into larger molecular structures, imparting unique properties.
Chemical Synthesis Reagent
This compound is employed in various organic transformations, acting as a versatile reagent for introducing fluorinated moieties. It is particularly useful in the construction of pharmacologically active molecules and advanced materials.
Material Science
The incorporation of fluorine atoms can modify the physical and chemical properties of materials. Ethyl difluoroacetate can be used in the synthesis of specialised polymers and other materials where enhanced stability or specific electronic properties are desired.
| Molecular weight | 124.09 |
|---|---|
| Linear formula | F2CHCO2C2H5 |
| Assay | 97% |
| Boiling point | 99.2 °C(lit.) |
| Density | 1.18 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.347(lit.) |
Hazard statements
- H226Flammable liquid and vapour
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 23 °C / 73.4 °F |
| Transport (UN / ADR) | UN 2924 8(3) / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 10-34 |
| Safety statements (S) | 16-26-27-36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl difluoroacetate primarily used for?
+
Ethyl difluoroacetate is primarily used as a building block and reagent in organic synthesis, particularly for introducing difluoromethyl groups into molecules for the development of pharmaceuticals, agrochemicals, and advanced materials.
What is the CAS number and formula for Ethyl difluoroacetate?
+
The CAS number for Ethyl difluoroacetate is 454-31-9, and its linear formula is F₂CHCO₂C₂H₅.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Ethyl difluoroacetate with an assay of 97%. This product is supplied for research and laboratory use and is not represented as USP, BP, EP, or any other pharmacopoeia grade.
What are the main safety hazards associated with Ethyl difluoroacetate?
+
Ethyl difluoroacetate is a flammable liquid and vapour (H226) and causes severe skin burns and eye damage (H314). It requires careful handling with appropriate personal protective equipment, including gloves, eye protection, and respiratory protection.
How is Ethyl difluoroacetate packed and exported?
+
Ethyl difluoroacetate is packed according to regulatory requirements for hazardous materials, including UN 2924, Class 8(3), Packing Group III. We facilitate global export for research and industrial needs.
How can I request a sample or quote for Ethyl difluoroacetate?
+
To request a sample or a quote for Ethyl difluoroacetate, please contact our sales team through the website or by phone, providing your specific requirements.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis