Ethyl diethoxyacetate
Ethyl diethoxyacetate (CAS: 6065-82-3) is an organic compound with the linear formula (C2H5O)2CHCOOC2H5 and a molecular weight of 176.21 g/mol. This ester, also known as glyoxylic acid ethyl ester diethyl acetal, is primarily utilised as a versatile building block in chemical synthesis. Its structure makes it valuable for introducing specific functional groups in the development of complex organic molecules, particularly in the pharmaceutical and fine chemical industries.
- IUPAC
- Glyoxylic acid ethyl ester diethyl acetal
- Synonyms
- Glyoxylic acid ethyl ester diethyl acetal

Organic Synthesis Intermediate
Ethyl diethoxyacetate serves as a key intermediate in the synthesis of various organic compounds. Its acetal and ester functionalities allow for diverse chemical transformations, making it useful in multi-step synthetic routes for pharmaceuticals and speciality chemicals.
Preparation of Analogs
This compound has been documented for use in the preparation of specific fatty acid analogs. For instance, it was employed in the synthesis of 12,13-dioxotetradecanoic acid di(N-methyl-thiosemicarbazone), a complex organic molecule.
Carbonyl Compound Chemistry
As a carbonyl compound featuring acetal protection, Ethyl diethoxyacetate is a valuable reagent for organic chemists exploring reactions involving carbonyl groups and protected aldehydes or their equivalents.
| Molecular weight | 176.21 |
|---|---|
| Linear formula | (C2H5O)2CHCOOC2H5 |
| Assay | 97% |
| Boiling point | 199 °C(lit.) |
| Density | 0.985 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.410(lit.) |
| Application | Ethyl diethoxyacetate was used in the preparation of a fatty acid analog containing DTS, 12,13-dioxotetradecanoic acid di(N-methyl-thiosemicarbazone) (FA-DTS)1. |
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 73 °C / 163.4 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 2 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Ethyl diethoxyacetate used for?
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Ethyl diethoxyacetate is primarily used as a building block in chemical synthesis, including the preparation of fatty acid analogs and other complex organic molecules.
What is the CAS number and formula for Ethyl diethoxyacetate?
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The CAS number for Ethyl diethoxyacetate is 6065-82-3, and its linear formula is (C2H5O)2CHCOOC2H5.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Ethyl diethoxyacetate with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
What are the safety and handling considerations for Ethyl diethoxyacetate?
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Ethyl diethoxyacetate is a combustible liquid (flash point 73°C). It requires handling with appropriate personal protective equipment, including eyeshields, gloves, and suitable respiratory protection (e.g., ABEK filter type).
How is Ethyl diethoxyacetate shipped or exported?
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Ethyl diethoxyacetate is classified as NA 1993 / PGIII for transport. Tech Serve Solutions, as an experienced global supplier, can arrange for its export worldwide.
How can I request a quote or sample for Ethyl diethoxyacetate?
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To request a quote or sample of Ethyl diethoxyacetate, please contact our sales team through the website or by phone.
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