Droperidol
Droperidol (CAS: 548-73-2, Formula: C22H22FN3O2, Molecular Weight: 379.43) is a butyrophenone derivative known for its potent dopamine D2 receptor antagonist activity. It also exhibits alpha-adrenergic blocking effects. Primarily recognized for its antiemetic properties and use in managing postoperative nausea and vomiting, Droperidol has also been explored for other neurological applications due to its influence on neurotransmitter systems. It is supplied for research and development purposes.
- IUPAC
- 1-[1-[3-(p-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl]-2-benzimidazolinone
Neurotransmitter Research
Droperidol serves as a valuable tool in neuroscience research, particularly for studying dopamine and adrenergic receptor pathways. Its antagonist properties aid in understanding the roles of these neurotransmitters in various physiological and pathological processes.
Antiemetic Agent Investigation
Historically used for its antiemetic effects, Droperidol is employed in research settings to investigate the mechanisms underlying nausea and vomiting. This includes studies on its efficacy and side-effect profiles in preclinical models.
GPCR Modulation Studies
As a modulator of G protein-coupled receptors (GPCRs), Droperidol is utilized in studies focusing on GPCR signaling pathways. This research is critical for understanding cellular communication and developing novel therapeutics targeting these receptors.
| Molecular weight | 379.43 |
|---|---|
| Empirical formula | C22H22FN3O2 |
| Storage temperature | 2-8°C |
Hazard statements
- H302Harmful if swallowed
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 22 |
| Safety statements (S) | 36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812), DRD2(1813), KCNH1(3756), KCNH2(3757) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Droperidol used for?
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Droperidol (CAS: 548-73-2, Formula: C22H22FN3O2) is primarily used in research settings to study dopamine and adrenergic receptor pathways, and its antiemetic properties. It is not for human or veterinary use.
What is the CAS number and formula for Droperidol?
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The CAS number for Droperidol is 548-73-2 and its empirical formula is C22H22FN3O2.
What grade and purity does Tech Serve Solutions supply for Droperidol?
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Tech Serve Solutions supplies Droperidol with a minimum assay of 98%. This product is intended for laboratory and research use only and is not represented as USP, BP, EP, or pharmaceutical grade.
How should Droperidol be handled safely?
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Droperidol is classified as harmful if swallowed (H302). When handling, ensure adequate ventilation and use appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves. Store at 2-8°C.
How is Droperidol packed and shipped?
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Droperidol is securely packaged for safe transport and is exported globally by Tech Serve Solutions, adhering to all relevant shipping regulations for research chemicals.
How can I request a quote or sample for Droperidol?
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To request a quote or sample of Droperidol, please contact our sales team via the website or email, providing your specific research requirements.
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