Doxepin hydrochloride

CAS 1229-29-4C19H21NO · HClBiochemicals & Reagents

Doxepin hydrochloride (CAS: 1229-29-4; Formula: C19H21NO · HCl; MW: 315.84 g/mol) is a dibenzoxepine derivative supplied by Tech Serve Solutions as a white to off-white powder. It functions as a biogenic amine transport inhibitor and is known for its activity in neuroscience research, particularly related to neurotransmission and cell signaling pathways. Its chemical structure and biological interactions make it a valuable tool for researchers investigating various physiological processes.

IUPAC: 11-(3-Dimethylaminopropylidene)-6,11-dihydrodibenz[b,e]oxepine hydrochloride

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Doxepin hydrochloride (C19H21NO · HCl) — chemical structure, CAS 1229-29-4; Life Science, fine chemical supplied by Tech Serve Solutions

Bioactive Small MoleculesBiochemicals and ReagentsBoehringer IngelheimCell BiologyDIG-DYGPCR ModulatorsGPCR ProteinsModulators and AntibodiesNeuroscienceNeurotransmission

01 /Applications

Neuroscience Research

Doxepin hydrochloride serves as a research chemical for investigating neurotransmitter systems, particularly the roles of biogenic amine transport and receptor modulation in neuronal function. It is utilized in studies concerning cell signaling and neurodegenerative diseases.

Biochemical Studies

As a bioactive small molecule, it is employed in biochemical assays to understand complex biological pathways. Its use in cell biology research aids in elucidating the mechanisms of cellular responses and interactions.

Pharmacological Tool

This compound acts as a valuable pharmacological tool for drug discovery and development. Researchers use it to probe G-protein coupled receptors (GPCRs) and their associated signaling cascades.

02 /Properties

Molecular weight	315.84
Empirical formula	C19H21NO · HCl
Assay	≥98% (GC)15% Z-isomer basis~85% E-isomer basis
Form	powder
Colour	white to off-white
Solubility	1 M HCl: soluble50 mg/mLH2O: soluble

03 /Safety & handling

GHS hazard pictogram: Toxic (GHS06) — Toxic

Danger

Hazard statements

H301Toxic if swallowed

Precautionary statements

P301IF SWALLOWED

Protective equipment	Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges
Transport (UN / ADR)	UN 2811 6.1 / PGIII
Water hazard class (WGK, DE)	3
Hazard codes (EU)	T
Risk statements (R)	25
Safety statements (S)	36/37/39-45

Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.

04 /Identifiers & registry

CAS number

1229-29-4

MDL number

MFCD00079135

PubChem substance

24278093

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is Doxepin hydrochloride used for?

Doxepin hydrochloride is used in research settings, particularly within neuroscience and cell biology, to study biogenic amine transport, neurotransmission, and G-protein coupled receptor (GPCR) modulation.

What is the CAS number and formula for Doxepin hydrochloride?

The CAS number for Doxepin hydrochloride is 1229-29-4, and its molecular formula is C19H21NO · HCl.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies Doxepin hydrochloride with an assay of ≥98% (GC), based on a mixture of Z-isomer (~15%) and E-isomer (~85%). We do not represent this product as USP, BP, or EP grade.

How should Doxepin hydrochloride be handled safely?

Doxepin hydrochloride is classified as toxic if swallowed (H301) and requires stringent safety precautions. Handling necessitates the use of eyeshields, faceshields, gloves, and a P2 respirator. Refer to the Safety Data Sheet for comprehensive handling instructions.

How is Doxepin hydrochloride packaged and shipped?

Doxepin hydrochloride is shipped as a UN 2811 hazardous material, class 6.1, packaging group III. Specific packaging details are available upon request.