DMT-dT Phosphoramidite

CAS 98796-51-1C40H49N4O8PChemical Synthesis

DMT-dT Phosphoramidite (CAS: 98796-51-1, C40H49N4O8P, MW: 744.81) is a crucial building block for DNA synthesis. Supplied as a white to off-white powder or granules, this reagent is configured for automated DNA synthesizers. With an assay of ≥99% by 31P-NMR and ≥99.0% by reversed-phase HPLC, it ensures high fidelity in oligonucleotide production. Sourced from non-animal origins, it is ideal for research and development in molecular biology and biotechnology.

IUPAC: 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite],DMT-dT amidite
Synonyms: 5′-O-(4,4′-dimethoxytrityl)-2′-deoxythymidine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite],DMT-dT amidite

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DMT-dT Phosphoramidite (C40H49N4O8P) — chemical structure, CAS 98796-51-1; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisDMT-dT PhosphoramiditeDNA AmiditesDNA PhosphoramiditesExpediteProligo ReagentsStandard DNA Amidites

01 /Applications

Oligonucleotide Synthesis

DMT-dT Phosphoramidite is a fundamental reagent for the solid-phase synthesis of DNA oligonucleotides. Its phosphoramidite chemistry enables efficient coupling to growing DNA chains on automated synthesizers, facilitating the creation of custom DNA sequences for research and diagnostic applications.

DNA Sequencing and Amplification

This compound is integral to the preparation of DNA primers and probes used in polymerase chain reaction (PCR) and DNA sequencing methodologies. Its high purity ensures reliable amplification and accurate sequencing results in molecular biology laboratories.

Biotechnology Research

As a key component in DNA synthesis, DMT-dT Phosphoramidite supports advancements in synthetic biology, genetic engineering, and therapeutic oligonucleotide development. It is suitable for use with systems like PerkinElmer 8900 and Polygen synthesizers.

02 /Properties

Molecular weight	744.81
Empirical formula	C40H49N4O8P
Assay	≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
Form	powder or granules
Colour	white to off-white
Storage temperature	2-8°C
Impurities tested	≤0.3 wt. % water content (Karl Fischer)
Biological source	from non-animal source

03 /Identifiers & registry

CAS number

98796-51-1

04 /Additional specifications

Type	for DNA synthesis
Product Line	Proligo Reagents
Packaging	pkg of 12 × 1 g (T111081-12)pkg of 12 × 2 g (T111082-12)
Applications	oligo synthesis: suitable
λ	conforms (UV/VIS Identity)
Compatibility	configured for PerkinElmer 8900configured for Polygen

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DMT-dT Phosphoramidite used for?

DMT-dT Phosphoramidite is primarily used as a building block for the synthesis of DNA oligonucleotides, essential for applications like DNA sequencing, PCR, and custom gene synthesis.

What is the CAS number and molecular formula?

The CAS number for DMT-dT Phosphoramidite is 98796-51-1, and its molecular formula is C40H49N4O8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies DMT-dT Phosphoramidite with an assay of ≥99% (31P-NMR) and ≥99.0% (reversed-phase HPLC). It is suitable for DNA synthesis and is from a non-animal source. Tech Serve Solutions does not represent this product as USP, BP, or EP grade.

What are the safety and handling precautions for DMT-dT Phosphoramidite?

DMT-dT Phosphoramidite has a WGK Germany classification of 3, indicating it is hazardous to water. Handle with appropriate personal protective equipment in a well-ventilated area to avoid inhalation or contact. Consult the Safety Data Sheet for detailed information.

How is DMT-dT Phosphoramidite packaged and shipped?

DMT-dT Phosphoramidite is available in packages of 12 × 1 g or 12 × 2 g. It is typically stored at 2-8°C and shipped according to standard chemical transport regulations. Tech Serve Solutions is a global supplier and exporter.

How can I request a quote or sample?

To request a quote or sample of DMT-dT Phosphoramidite, please contact our sales team through the TSS website or directly via email, providing your specific requirements and delivery details.