DMT-dG(ib) Phosphoramidite

CAS 93183-15-4C44H54N7O8PChemical Synthesis

DMT-dG(ib) Phosphoramidite (CAS: 93183-15-4, C44H54N7O8P) is a key reagent for DNA synthesis, manufactured with high purity. This phosphoramidite derivative of deoxyguanosine, protected with a dimethoxytrityl (DMT) group and an isobutyryl (ib) protecting group on the N2 position, is essential for solid-phase oligonucleotide synthesis. Its reliable performance ensures the integrity of synthetic DNA strands.

IUPAC: DMT-dG(ib) amidite,N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]
Synonyms: N2-Isobutyryl-5′-O-(4,4′-dimethoxytrityl)-2′-deoxyguanosine-3′-O-[O-(2-cyanoethyl)-N,N′-diisopropylphosphoramidite]

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DMT-dG(ib) Phosphoramidite (C44H54N7O8P) — chemical structure, CAS 93183-15-4; Chemistry, fine chemical supplied by Tech Serve Solutions

Chemical SynthesisDMT-dG(ib) PhosphoramiditeDNA AmiditesDNA PhosphoramiditesExpediteProligo ReagentsStandard DNA Amidites

01 /Applications

Oligonucleotide Synthesis

This phosphoramidite is specifically configured for automated solid-phase DNA synthesis, enabling the precise incorporation of modified guanine bases into oligonucleotide chains.

DNA Sequencing and Genotyping

Used in the preparation of custom DNA probes and primers essential for various molecular biology applications, including sequencing and genotyping assays.

Chemical Biology Research

Facilitates the creation of modified DNA molecules for research into DNA structure, function, and interactions with biological systems.

02 /Properties

Molecular weight	839.92
Empirical formula	C44H54N7O8P
Assay	≥99% (31P-NMR)≥99.0% (reversed phase HPLC)
Form	powder or granules
Colour	white to off-white
Storage temperature	2-8°C
Impurities tested	≤0.3 wt. % water content (Karl Fischer)
Biological source	from non-animal source

03 /Identifiers & registry

CAS number

93183-15-4

04 /Additional specifications

Type	for DNA synthesis
Product Line	Proligo Reagents
Packaging	pkg of 12 × 1 g (G111081-12)pkg of 12 × 2 g (G111082-12)
Applications	oligo synthesis: suitable
λ	conforms (UV/VIS Identity)
Compatibility	configured for PerkinElmer 8900configured for Polygen

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DMT-dG(ib) Phosphoramidite used for?

DMT-dG(ib) Phosphoramidite is primarily used in solid-phase automated DNA synthesis to incorporate modified guanine bases into synthetic oligonucleotides.

What is the CAS number and chemical formula for DMT-dG(ib) Phosphoramidite?

The CAS number is 93183-15-4 and the chemical formula is C44H54N7O8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies DMT-dG(ib) Phosphoramidite with an assay of ≥99% (31P-NMR) and ≥99.0% (reversed phase HPLC). This is a research-grade material and is not represented as USP, BP, EP, or other pharmacopoeia grades.

How should DMT-dG(ib) Phosphoramidite be handled and stored?

According to the safety data, this compound has a WGK Germany classification of 3, indicating it is hazardous to water. It should be stored at 2-8°C. Handle with appropriate personal protective equipment in a well-ventilated area.