Dansylhydrazine
Dansylhydrazine (CAS: 33008-06-9) is a valuable chemical reagent with the molecular formula (CH3)2NC10H6SO2NHNH2 and a molecular weight of 265.33 g/mol. It is primarily recognised for its utility as a fluorometric derivatization agent for carbonyl compounds. Its ability to react with aldehydes allows for the subsequent separation and identification of these compounds using various analytical techniques, making it a key component in analytical chemistry.
- IUPAC
- 5-(Dimethylamino)-1-naphthalenesulfonic hydrazide,5-(Dimethylamino)naphthalene-1-sulfonohydrazide,Dns-Hz
- Synonyms
- 5-(Dimethylamino)-1-naphthalenesulfonohydrazide5-(Dimethylamino)naphthalene-1-sulfonohydrazideDns-Hz
Fluorometric Derivatization of Carbonyls
Dansylhydrazine serves as an effective fluorometric reagent for the detection and quantification of aldehyde compounds. Upon reaction, it forms stable dansylated derivatives that exhibit fluorescence, enabling sensitive analysis.
Analytical Separations
The dansylated carbonyl derivatives produced using Dansylhydrazine can be readily separated and identified using chromatographic techniques. This application is crucial in complex mixture analysis where sensitive detection of trace aldehydes is required.
Chromatography and Spectroscopy
Dansylhydrazine is employed as a labelling reagent for carbohydrates and other carbonyl-containing molecules, particularly for enhanced detection in High-Performance Liquid Chromatography (HPLC) and spectroscopic analysis due to its fluorescent properties.
| Molecular weight | 265.33 |
|---|---|
| Linear formula | (CH3)2NC10H6SO2NHNH2 |
| Assay | ≥90% (HPLC) |
| Solubility | ethanol: soluble |
| Storage temperature | 2-8°C |
| Application | Dansylhydrazine (DH) is widely used as a fluorometric reagent for carbonyl compounds. Dansylated carbonyl molecules can be separated and identified by analytical techniques. |
| Suitability | suitable for fluorescence |
| Melting point | 126-130 °C(lit.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36/37 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Product Line | BioReagent |
|---|---|
| Fluorescence | λex 340 nm; λem 525 nm in ethanol |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dansylhydrazine used for?
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Dansylhydrazine is primarily used as a fluorometric derivatization reagent for carbonyl compounds, allowing for their sensitive detection and analysis through separation techniques like chromatography.
What are the CAS number and molecular formula for Dansylhydrazine?
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The CAS number for Dansylhydrazine is 33008-06-9, and its molecular formula is (CH3)2NC10H6SO2NHNH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dansylhydrazine with an assay of ≥90% (HPLC). This product is not represented as USP, BP, or EP grade.
How should Dansylhydrazine be handled safely?
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Dansylhydrazine is a warning substance that may cause skin irritation (H315), serious eye irritation (H319), and respiratory irritation (H335). It should be handled with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area.
How is Dansylhydrazine packed and shipped by TSS?
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Dansylhydrazine is typically stored at 2-8°C. Tech Serve Solutions can export this chemical, adhering to all relevant shipping regulations for chemical compounds.
How can I request a quote or sample for Dansylhydrazine?
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To request a quote or a sample of Dansylhydrazine, please contact the Tech Serve Solutions sales team through our website or by telephone.
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