DMT-dC(tac) Phosphoramidite
DMT-dC(tac) Phosphoramidite (CAS: 149989-59-3, Formula: C51H62N5O9P) is a critical reagent for automated DNA synthesis. Supplied by Tech Serve Solutions, this phosphoramidite is specifically designed for incorporation into oligonucleotide chains, enabling the creation of custom DNA sequences for research and development. Its formulation is optimised for efficient coupling and deprotection in standard automated synthesizers.
- IUPAC
- DMT-dC(tac) amidite
Oligonucleotide Synthesis
DMT-dC(tac) Phosphoramidite is a key building block for the automated synthesis of DNA strands. It is compatible with standard DNA synthesizers, facilitating the precise assembly of custom oligonucleotides for various research applications.
DNA Amidite Chemistry
This compound belongs to the class of DNA amidites, which are essential reagents in solid-phase DNA synthesis. Its phosphoramidite functionality allows for controlled chain elongation on a solid support.
Fast Deprotection Applications
The 'tac' (thioacetyl) protection group on the exocyclic amine of cytosine is designed for rapid and efficient deprotection. This characteristic is beneficial in high-throughput or time-sensitive oligonucleotide synthesis workflows.
| Empirical formula | C51H62N5O9P |
|---|---|
| Assay | ≥98% (31P-NMR)≥98.0% (reversed phase HPLC) |
| Storage temperature | −20°C |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Type | for DNA synthesis |
|---|---|
| Product Line | Proligo Reagents |
| Packaging | pkg of 1 × 10 g (C112010-01)pkg of 6 × 5 g C112005-06 |
| Applications | oligo synthesis: suitable |
| λ | conforms (UV/VIS Identity) |
| Compatibility | configured for |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is DMT-dC(tac) Phosphoramidite used for?
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DMT-dC(tac) Phosphoramidite is primarily used as a reagent in automated DNA synthesis for the incorporation of cytosine into oligonucleotide sequences.
What are the CAS number and empirical formula of this compound?
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The CAS number for DMT-dC(tac) Phosphoramidite is 149989-59-3, and its empirical formula is C51H62N5O9P.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies DMT-dC(tac) Phosphoramidite with an assay of ≥98% (31P-NMR) and ≥98.0% (reversed phase HPLC). This product is supplied for research and development purposes and is not intended for USP, BP, EP, or other pharmacopoeia applications.
What are the safety and handling recommendations for DMT-dC(tac) Phosphoramidite?
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Handling DMT-dC(tac) Phosphoramidite requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. This compound has a WGK Germany rating of 3, indicating it is hazardous.
How is DMT-dC(tac) Phosphoramidite packaged and shipped?
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DMT-dC(tac) Phosphoramidite is available in packages of 1 x 10 g (C112010-01) and 6 x 5 g (C112005-06). It is stored at -20°C. Tech Serve Solutions exports fine chemicals globally.
How can I request a sample or quote for DMT-dC(tac) Phosphoramidite?
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To request a sample or obtain a quotation for DMT-dC(tac) Phosphoramidite, please contact the Tech Serve Solutions sales department through our website or by phone.
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