DMT-dA(tac) Phosphoramidite

CAS 149989-58-2C52H62N7O8PChemical Synthesis

DMT-dA(tac) Phosphoramidite (CAS: 149989-58-2; Formula: C52H62N7O8P; MW: 944.06) is a critical reagent for DNA synthesis. As a high-purity phosphoramidite, it is specifically designed for use in automated DNA synthesizers, enabling the efficient and reliable incorporation of adenine nucleosides into oligonucleotide chains. Its formulation ensures compatibility with standard synthesis protocols, facilitating research and development in molecular biology and related fields.

IUPAC: DMT-dA(tac) amidite
Synonyms: DMT-dA(tac) amidite5'-O-Dimethoxytrityl-N4-acetyl-deoxyadenosine-3'-O-(β-cyanoethyl-N,N-diisopropyl)phosphoramidite

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DMT-dA(tac) Phosphoramidite (C52H62N7O8P) — chemical structure, CAS 149989-58-2; Chemistry, fine chemical supplied by Tech Serve Solutions

ABI 3900ABI 39XChemical SynthesisDMT-dA(tac) PhosphoramiditeDNA AmiditesDNA PhosphoramiditesProligo Reagents

01 /Applications

Oligonucleotide Synthesis

DMT-dA(tac) Phosphoramidite is suitable for the automated synthesis of DNA oligonucleotides. It is configured for compatibility with ABI synthesizers, allowing for the efficient incorporation of modified adenine bases into synthetic DNA strands.

Chemical Synthesis

This compound serves as a key building block in chemical synthesis, particularly for creating complex nucleic acid structures. Its phosphoramidite chemistry is integral to solid-phase DNA synthesis methodologies.

Research and Development

Utilised in research settings to generate custom DNA sequences for applications in genomics, diagnostics, and synthetic biology. Its high purity ensures reliable results in demanding research projects.

02 /Properties

Molecular weight	944.06
Empirical formula	C52H62N7O8P
Assay	≥98% (31P-NMR)≥98.0% (reversed phase HPLC)
Storage temperature	−20°C

03 /Identifiers & registry

CAS number

149989-58-2

04 /Additional specifications

Type	for DNA synthesis
Product Line	Proligo Reagents
Packaging	pkg of 12 × 1 g (A112031-12)pkg of 12 × 2 g (A112032-12)pkg of 12 × 4 g (A112064-12)
Applications	oligo synthesis: suitable
λ	conforms (UV/VIS Identity)
Compatibility	configured for ABI

05 /Quality & supply

Documentation

Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.

Supply & logistics

Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.

06 /Frequently asked questions

What is DMT-dA(tac) Phosphoramidite used for?

DMT-dA(tac) Phosphoramidite is primarily used for the synthesis of DNA oligonucleotides, serving as a crucial building block in automated DNA synthesizers and chemical synthesis applications.

What are the CAS number and formula for DMT-dA(tac) Phosphoramidite?

The CAS number is 149989-58-2, and the empirical formula is C52H62N7O8P.

What grade and purity does Tech Serve Solutions supply?

Tech Serve Solutions supplies DMT-dA(tac) Phosphoramidite with an assay of ≥98% (31P-NMR) and ≥98.0% (reversed phase HPLC). It is not represented as USP, BP, or EP grade.

What are the safety and handling recommendations for this product?

This product has a WGK Germany rating of 3, indicating it is hazardous. Handle with appropriate personal protective equipment in a well-ventilated area. Refer to the Safety Data Sheet for detailed hazard information and handling procedures.

How is DMT-dA(tac) Phosphoramidite packaged and shipped?

DMT-dA(tac) Phosphoramidite is available in various packaging sizes, including 1g, 2g, and 4g units, supplied in packs of 12. It is stored at -20°C and suitable for export.

How can I request a sample or quote for DMT-dA(tac) Phosphoramidite?

To request a sample or a quotation for DMT-dA(tac) Phosphoramidite, please contact our sales team through the Tech Serve Solutions website or by phone.