Diphosphoryl chloride
Diphosphoryl chloride (CAS 13498-14-1), with the molecular formula Cl2P(O)OP(O)Cl2 and a molecular weight of 251.76 g/mol, is a reactive phosphorus compound. It serves as a valuable reagent in organic synthesis, particularly noted for its utility in Vilsmeier formylation and glyoxylation reactions involving nucleophilic aromatic substrates. This compound is essential for various chemical transformations.
- IUPAC
- Diphosphoric tetrachloride,Pyrophosphoric tetrachloride,Pyrophosphoryl chloride
Vilsmeier Formylation Reagent
Diphosphoryl chloride is employed as a key reagent in Vilsmeier formylation reactions. It facilitates the introduction of formyl groups onto nucleophilic aromatic compounds, a crucial step in the synthesis of various organic molecules.
Glyoxylation Reactions
This compound is also useful in glyoxylation reactions. It enables the addition of glyoxyl functionalities to aromatic systems, expanding its utility in complex organic synthesis pathways.
Phosphorus Precursor
As a phosphorus-containing compound, Diphosphoryl chloride can act as a precursor in the synthesis of other organophosphorus compounds, finding applications in materials science and specialised chemical manufacturing.
| Molecular weight | 251.76 |
|---|---|
| Linear formula | Cl2P(O)OP(O)Cl2 |
| Assay | 97% |
| Boiling point | 90 °C/12 mmHg(lit.) |
| Density | 1.82 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.475(lit.) |
| Application | Useful reagent for the Vilsmeier formylation and glyoxylation reactions of nucleophilic aromatic compounds.1 |
Hazard statements
- H314Causes severe skin burns and eye damage
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Transport (UN / ADR) | UN 3264 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 14-34 |
| Safety statements (S) | 26-36/37/39-45 |
| Supplemental hazards | Reacts violently with water. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diphosphoryl chloride used for?
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Diphosphoryl chloride is primarily used as a reagent for Vilsmeier formylation and glyoxylation reactions of nucleophilic aromatic compounds.
What are the CAS number and formula for Diphosphoryl chloride?
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The CAS number for Diphosphoryl chloride is 13498-14-1, and its formula is Cl2P(O)OP(O)Cl2.
What grade and purity does Tech Serve Solutions supply for Diphosphoryl chloride?
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Tech Serve Solutions typically supplies Diphosphoryl chloride with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Diphosphoryl chloride be handled safely?
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Diphosphoryl chloride reacts violently with water and is corrosive. Handle with extreme caution, wearing appropriate personal protective equipment including face shields, gloves, and suitable respirators. Ensure adequate ventilation and avoid contact with water.
How is Diphosphoryl chloride packed and shipped?
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Diphosphoryl chloride is shipped according to UN 3264, Hazard Class 8, Packing Group II regulations, reflecting its corrosive nature. Packing is designed to ensure safe transport and handling.
How can I request a quote or sample of Diphosphoryl chloride?
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To request a quote or a sample of Diphosphoryl chloride, please contact our sales team through the website or by phone, providing your specific requirements.
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