Diethyl phenylmalonate
Diethyl phenylmalonate (CAS: 83-13-6), with the molecular formula C12H14O4 and a molecular weight of 236.26 g/mol, is a valuable organic compound. It serves as a key building block in chemical synthesis, particularly for esters and carbonyl compounds. This malonate derivative is essential for various research and development applications, enabling the creation of more complex molecular structures.
Pharmaceutical Intermediate Synthesis
Diethyl phenylmalonate is utilised as a precursor in the synthesis of pharmaceutical compounds. For example, it has been employed in the preparation of deuterated analogues of active pharmaceutical ingredients, such as felbamate-d4.
Organic Synthesis Reagent
As a functionalised malonate ester, this compound is a versatile reagent in organic chemistry laboratories. It participates in various carbon-carbon bond-forming reactions crucial for constructing complex organic molecules.
Building Block for Complex Molecules
Its structure, featuring an active methylene group and two ester functionalities, makes diethyl phenylmalonate an ideal starting material for synthesising diverse chemical entities.
| Molecular weight | 236.26 |
|---|---|
| Linear formula | C6H5CH(COOC2H5)2 |
| Assay | 98% |
| Boiling point | 170-172 °C/14 mmHg(lit.) |
| Density | 1.095 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.491(lit.) |
| Application | Diethyl phenylmalonate was used in the synthesis of felbamate-d4 (2-phenyl-1,3-propanediol-l,l,3,3-d4 dicarbamate) using lithium aluminum deuteride1. |
| Melting point | 16 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, half-mask respirator (EU), half-mask respirator (US), multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | 113 °C / 235.4 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl phenylmalonate used for?
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Diethyl phenylmalonate is used as a building block in organic synthesis, particularly for creating esters and carbonyl compounds, and as an intermediate in pharmaceutical synthesis.
What is the CAS number and chemical formula for Diethyl phenylmalonate?
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The CAS number for Diethyl phenylmalonate is 83-13-6, and its linear formula is C6H5CH(COOC2H5)2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl phenylmalonate with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Diethyl phenylmalonate be handled safely?
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Handling Diethyl phenylmalonate requires appropriate personal protective equipment, including eyeshields, gloves, and respiratory protection. It is combustible and should be kept away from heat and open flames. Consult the Safety Data Sheet for full details.
How is Diethyl phenylmalonate packed and exported?
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Diethyl phenylmalonate is carefully packed to maintain its integrity during transit and is expertly exported globally by Tech Serve Solutions.
How can I request a quote or sample of Diethyl phenylmalonate?
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To request a quote or sample, please contact the Tech Serve Solutions sales team via our website or direct inquiry channels.
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