Diethyl oxalpropionate
Diethyl oxalpropionate (CAS 759-65-9) is an ester with the molecular formula C₂H₅OCOCH(CH₃)COCOOC₂H₅ and a molecular weight of 202.20 g/mol. This compound serves as a valuable building block in organic synthesis. It is primarily utilised as a reactant in the preparation of diverse chemical entities, including potential anticancer and antiviral agents, functional polyesters, and specific enzyme inhibitors.
- IUPAC
- Diethyl 2-methyl-3-oxosuccinate,Methyloxo-butanedioic acid diethyl ester,NSC 33946
- Synonyms
- Diethyl 2-methyl-3-oxosuccinateMethyloxo-butanedioic acid diethyl esterNSC 33946
Synthesis of Pharmaceutical Agents
Diethyl oxalpropionate is employed as a key intermediate in the synthesis of various biologically active compounds, including anticancer and antiviral agents, as well as calpain inhibitors and human A2A receptor antagonists.
Preparation of Functional Polyesters
This ester is used as a monomer precursor for the creation of specialised polymers. These functional polyesters can be designed for various material science applications.
Organic Synthesis Reagent
As a versatile carbonyl compound, diethyl oxalpropionate participates in oxidation reactions, for example, with organohypervalent iodine reagents, contributing to diverse synthetic pathways.
Biochemical Research
The compound has been utilised in structural studies, such as those investigating dihydropteroate synthase inhibitors, aiding in the understanding of enzyme mechanisms.
| Molecular weight | 202.20 |
|---|---|
| Linear formula | C2H5OCOCH(CH3)COCOOC2H5 |
| Assay | ≥95.0% (GC) |
| Grade | purum |
| Boiling point | 138 °C/23 mmHg(lit.) |
| Density | 1.073 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.432(lit.)n20/D 1.433 |
| Application | Reactant involved in:• Synthesis of anticancer and antiviral agents1• Oxidation by organohypervalent iodine reagent2• Synthesis of monomers for preparation of functional polyesters3• Synthesis of calpain inhibitors4• Preparation of human A2A receptor antagonists5• Structural studies of dihydropteroate synthase inhibitors6 |
| Protective equipment | Eyeshields, Gloves |
|---|---|
| Flash point | 97 °C / 206.6 °F |
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl oxalpropionate used for?
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Diethyl oxalpropionate is used as a reactant in the synthesis of anticancer and antiviral agents, monomers for functional polyesters, calpain inhibitors, human A2A receptor antagonists, and in oxidation reactions. It also features in structural studies of enzyme inhibitors.
What are the CAS number and formula for Diethyl oxalpropionate?
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The CAS number for Diethyl oxalpropionate is 759-65-9, and its linear formula is C₂H₅OCOCH(CH₃)COCOOC₂H₅.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Diethyl oxalpropionate with a purity of ≥95.0% (GC) and a grade of 'purum'. TSS does not represent this product as USP, BP, EP or other pharmacopoeia grades.
How should Diethyl oxalpropionate be handled safely?
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When handling Diethyl oxalpropionate, it is recommended to wear eyeshields and gloves. The compound has a flash point of 97 °C (206.6 °F) and is classified under WGK Germany 3.
Is Diethyl oxalpropionate a controlled substance?
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The provided data does not indicate that Diethyl oxalpropionate (CAS 759-65-9) is a controlled substance.
How is Diethyl oxalpropionate packed and shipped?
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Tech Serve Solutions, as a global supplier and exporter, ensures appropriate packaging and shipping for Diethyl oxalpropionate, adhering to all relevant regulations for chemical transport.
How can I request a quote or sample for Diethyl oxalpropionate?
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To request a quote or a sample of Diethyl oxalpropionate, please contact our sales department through the website or by phone.
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