Diethyl phenyl orthoformate
Diethyl phenyl orthoformate (CAS: 14444-77-0; Formula: CH(OC2H5)2OC6H5; MW: 196.24 g/mol) is an organic compound belonging to the orthoester class. This chemical serves as a valuable building block in organic synthesis. It is particularly useful as a reagent in the preparation of various heterocyclic compounds and as a protecting group in organic chemistry due to its acetal-like structure.
Organic Synthesis Intermediate
Diethyl phenyl orthoformate functions as a versatile intermediate in the synthesis of complex organic molecules. Its reactivity allows for its incorporation into various synthetic pathways, facilitating the construction of novel chemical entities.
Heterocyclic Chemistry
This orthoester is employed in the synthesis of diverse heterocyclic compounds. Its structure can be leveraged to introduce specific functional groups or ring systems required in pharmaceutical and material science research.
Protecting Group Chemistry
Due to its acetal functionality, Diethyl phenyl orthoformate can act as a protecting group for diols and other functionalities during multi-step organic syntheses. It can be selectively cleaved under appropriate conditions.
| Molecular weight | 196.24 |
|---|---|
| Linear formula | CH(OC2H5)2OC6H5 |
| Assay | ≥97.0% |
| Boiling point | 103-104 °C/10 mmHg(lit.) |
| Density | 1.014 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.480(lit.)n20/D 1.480 |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
Precautionary statements
- P305IF IN EYES
| Protective equipment | Eyeshields, full-face respirator (US), Gloves, multi-purpose combination respirator cartridge (US), type ABEK (EN14387) respirator filter |
|---|---|
| Flash point | 65 °C / 149 °F |
| Transport (UN / ADR) | NA 1993 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/38 |
| Safety statements (S) | 26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Diethyl phenyl orthoformate used for?
+
Diethyl phenyl orthoformate is primarily used as a versatile building block and intermediate in organic synthesis, particularly in the preparation of heterocyclic compounds and as a protecting group.
What are the CAS number and molecular formula for Diethyl phenyl orthoformate?
+
The CAS number for Diethyl phenyl orthoformate is 14444-77-0, and its molecular formula is CH(OC2H5)2OC6H5.
What grade and purity does Tech Serve Solutions supply?
+
Tech Serve Solutions supplies Diethyl phenyl orthoformate with an assay of ≥97.0%. We do not represent this product as USP, BP, or EP grade.
How should Diethyl phenyl orthoformate be handled safely?
+
Diethyl phenyl orthoformate is a warning-level hazardous substance (GHS07). It can cause skin irritation (H315) and serious eye irritation (H319). Ensure adequate ventilation and wear appropriate personal protective equipment, including eyeshields and gloves. Avoid breathing vapours or mist. In case of contact, rinse cautiously with water for several minutes and seek medical advice if irritation persists.
Does Tech Serve Solutions export Diethyl phenyl orthoformate?
+
Yes, Tech Serve Solutions is a specialist global supplier and exporter of fine chemicals, including Diethyl phenyl orthoformate. We can fulfil export requirements for research and industrial purposes.
How can I request a quote or sample for Diethyl phenyl orthoformate?
+
To request a quote or sample for Diethyl phenyl orthoformate, please contact our sales team through the website or by phone, providing your specific requirements and delivery details.
▶ Related products
1-(2-Fluorobenzyl)piperazine
C11H15FN2
Chemical Synthesis
1-(2-Fluorophenyl)biguanide hydrochloride
Chemical Synthesis
1-(2-Fluorophenyl)cyclopropanecarboxylic acid
C10H9FO2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine
C10H13FN2
Chemical Synthesis
1-(2-Fluorophenyl)piperazine monohydrochloride
C10H13FN2 · HCl
Chemical Synthesis
1-(2-Furoyl)-1H-benzotriazole
C11H7N3O2
Chemical Synthesis
1-(2-Furoyl)piperazine
C9H12N2O2
Chemical Synthesis
1-(2-Hydroxy-5-methylphenyl)-3-phenyl-1,3-propanedione
Chemical Synthesis
▶ Explore more
3-Methyl-1,5-di-p-tolyl-1,4-pentazadiene
Chemical Synthesis
3-Methyl-1,5-pentanediol
Chemical Synthesis
3-Methyl-1-(2-methylphenyl)-1H-pyrazol-5-amine
C11H13N3
Chemical Synthesis
3-Methyl-1-(3′-sulfoamidophenyl)-5-pyrazolone
C10H11N3O3S
Chemical Synthesis