Cyclopropylamine
Cyclopropylamine (CAS: 765-30-0), with the molecular formula C3H5NH2 and a molar mass of 57.09 g/mol, is a primary amine characterised by its cyclopropyl ring. This versatile organic building block is employed in various chemical synthesis applications, particularly in the development of pharmaceutical intermediates and novel organic compounds. Its reactive nature makes it a valuable reagent in advanced organic chemistry.
- IUPAC
- Aminocyclopropane
- Synonyms
- AminocyclopropaneCyclopropane, amino-
Synthesis of Pharmaceutical Intermediates
Cyclopropylamine serves as a key intermediate in the synthesis of complex organic molecules, including potential pharmaceutical agents. It has been utilized in the preparation of N-[4-(4-fluoro)phenyl-2-aminothiazol-5-yl]pyrimidin-2-yl-alkylamine derivatives.
Organometallic Complex Synthesis
This amine can be incorporated into organometallic complexes. For example, it has been used in the synthesis of platinum complexes such as Pt(CPA)2(bis-methylthiomethylenepropanedioate) and Pt(CPA)2(bis-ethylthiomethylenepropanedioate).
Organic Synthesis Building Block
As a fundamental organic building block, cyclopropylamine is valuable for introducing the cyclopropylamino moiety into various organic structures, facilitating the exploration of new chemical entities.
| Molecular weight | 57.09 |
|---|---|
| Linear formula | C3H5NH2 |
| Assay | 98% |
| Boiling point | 49-50 °C(lit.) |
| Density | 0.824 g/mL at 25 °C(lit.) |
| Refractive index | n20/D 1.420(lit.) |
| Vapour pressure | 4.67 psi (20 °C) |
| Autoignition temp | 527 °F |
| Application | Cyclopropylamine(CPA) has been used in the synthesis of N-[4-(4-fluoro)phenyl-2-aminothiazol-5-yl]pyrimidin-2-yl-alkylamine derivatives1. It has been used in the synthesis of Pt(CPA)2(bismethylthiomethylenepropanedioate) and Pt(CPA)2(bisethylthiomethylenepropanedioate) complexes2. |
Hazard statements
- H225Highly flammable liquid and vapour
- H302Harmful if swallowed
- H314Causes severe skin burns and eye damage
Precautionary statements
- P210Keep away from heat, sparks and open flames. No smoking
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Faceshields, full-face respirator (US), Gloves, Goggles, multi-purpose combination respirator cartridge (US) |
|---|---|
| Flash point | -26 °C / -14.8 °F |
| Transport (UN / ADR) | UN 2733 3/PG 2 |
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | F,C |
| Risk statements (R) | 11-22-34 |
| Safety statements (S) | 16-26-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Cyclopropylamine (CAS 765-30-0) used for?
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Cyclopropylamine is primarily used as a building block in organic synthesis, including the preparation of pharmaceutical intermediates and novel organic compounds. It has been employed in the synthesis of specific amine and platinum-containing derivatives.
What is the CAS number and molecular formula for Cyclopropylamine?
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The CAS number for Cyclopropylamine is 765-30-0, and its molecular formula is C3H5NH2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Cyclopropylamine with an assay of 98%. We do not represent this product as USP, BP, or EP grade.
How should Cyclopropylamine be handled safely?
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Cyclopropylamine is a dangerous substance classified with GHS hazards including H225 (Highly flammable liquid and vapour), H302 (Harmful if swallowed), and H314 (Causes severe skin burns and eye damage). Handle with appropriate personal protective equipment, including gloves, goggles, and face shields, in a well-ventilated area, and keep away from ignition sources. Refer to the Safety Data Sheet for comprehensive handling instructions.
How is Cyclopropylamine packed, shipped, and exported?
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Tech Serve Solutions offers expert packing, shipping, and exporting of chemicals globally, ensuring compliance with all relevant regulations for hazardous materials like Cyclopropylamine (UN 2733).
How can I request a sample or quote for Cyclopropylamine?
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To request a sample or quote for Cyclopropylamine, please contact our sales team through the website or by phone, providing your specific requirements.
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