Dess-Martin periodinane
Dess-Martin periodinane (CAS: 87413-09-0), with the molecular formula C13H13IO8 and a molecular weight of 424.14 g/mol, is a hypervalent iodine compound primarily employed as a selective oxidizing agent. It is widely used in organic synthesis for the mild and efficient oxidation of primary and secondary alcohols to their corresponding aldehydes and ketones under ambient conditions, making it a valuable reagent in complex molecule synthesis.
- IUPAC
- 1,1,1-Tris(acetyloxy)-1,1-dihydro-1,2-benziodoxol-3-(1H)-one
- Synonyms
- 1,1,1-Tris(acetyloxy)-1,1-dihydro-1,2-benziodoxol-3-(1H)-one
Oxidation of Alcohols
Dess-Martin periodinane is a highly effective reagent for oxidizing primary alcohols to aldehydes and secondary alcohols to ketones. This transformation occurs under mild conditions, preserving sensitive functional groups elsewhere in the molecule.
Selective Oxidation
Its selectivity allows for the oxidation of alcohols in the presence of other oxidizable functionalities, making it a preferred choice in multi-step syntheses where chemoselectivity is critical.
Aldehyde Synthesis
The reagent is particularly useful for generating aldehydes from primary alcohols, often providing higher yields and cleaner reactions compared to harsher oxidizing agents.
| Molecular weight | 424.14 |
|---|---|
| Empirical formula | C13H13IO8 |
| Assay | 97% |
| Boiling point | 40 °C |
| Density | 1.369 g/mL at 25 °C |
| Concentration | 0.3 M in methylene chloride |
| Storage temperature | −20°C |
| Melting point | 130-133 °C(lit.) |
| Application | Oxidizing agent for 1° and 2° alcohols to aldehydes and ketones.1,2 |
Hazard statements
- H272May intensify fire; oxidiser
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H315Causes skin irritation
- H319Causes serious eye irritation
- H332Harmful if inhaled
- H335May cause respiratory irritation
Precautionary statements
- P220Keep away from clothing and combustible materials
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 1479 5.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | O,Xn |
| Risk statements (R) | 8-20/21/22-36/37/38-44 |
| Safety statements (S) | 26-36 |
| Supplemental hazards | Risk of explosion if heated under confinement. |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Dess-Martin periodinane used for?
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Dess-Martin periodinane is primarily used as a selective oxidizing agent for the oxidation of primary and secondary alcohols to aldehydes and ketones, respectively. It is valued for its mild reaction conditions and high chemoselectivity.
What is the CAS number and formula for Dess-Martin periodinane?
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The CAS number for Dess-Martin periodinane is 87413-09-0, and its molecular formula is C13H13IO8.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Dess-Martin periodinane with an assay of 97%. We do not represent this product as USP, BP, or EP grade.
How should Dess-Martin periodinane be handled safely?
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Dess-Martin periodinane is an oxidizer and can cause irritation. It carries a risk of explosion if heated under confinement. Handle with appropriate personal protective equipment, including a dust mask (type N95), eyeshields, and gloves, in a well-ventilated area. Refer to the safety data sheet for comprehensive handling guidelines.
Is Dess-Martin periodinane a controlled substance?
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The provided data does not indicate that Dess-Martin periodinane is a controlled substance.
How is Dess-Martin periodinane packed and shipped?
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Dess-Martin periodinane is typically shipped under conditions suitable for oxidising agents (UN 1479 5.1 / PGIII), and stored at -20°C to maintain its stability. Specific packaging details for export are available upon request.
How can I request a sample or quote for Dess-Martin periodinane?
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To request a sample or a quote for Dess-Martin periodinane, please contact our sales department through the TSS website or by phone.
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