Desyl bromide
Desyl bromide (CAS: 1484-50-0) is a chemical compound with the linear formula C6H5CH(Br)COC6H5. It is classified as a ketone and a carbonyl compound, often used as a building block in organic synthesis. Its utility is demonstrated in the preparation of phosphate esters and in developing novel chemiluminogenic reactions for peptide analysis. Supplied by TSS, it adheres to a purity level of 97%.
- IUPAC
- 2-Bromo-2-phenylacetophenone
- Synonyms
- 2-Bromo-2-phenylacetophenone

Synthesis of Phosphate Esters
Desyl bromide has been employed in the synthesis of phosphate esters derived from benzoin and benzoinyl N-carbobenzyloxyglycylphenylalanate.
Chemiluminogenic Reactions
It serves as a reagent in novel chemiluminogenic reactions, enabling sensitive determination of Arg-containing peptides.
Organic Synthesis
As a versatile building block, desyl bromide is valuable in various organic synthesis pathways, particularly for creating complex molecules.
| Molecular weight | 275.14 |
|---|---|
| Linear formula | C6H5CH(Br)COC6H5 |
| Assay | 97% |
| Application | Desyl bromide has been used in:• synthesis of phosphate esters of benzoin and benzoinyl N-carbobenzyloxyglycylphenylalanate1• novel chemiluminogenic reaction for the sensitive determination of Arg-containing peptides2 |
| Melting point | 56-58 °C(lit.) |


Hazard statements
- H314Causes severe skin burns and eye damage
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P280Wear protective gloves, clothing and eye/face protection
- P305IF IN EYES
- P310Immediately call a POISON CENTER or doctor
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 3261 8 / PGII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | C |
| Risk statements (R) | 34-36/37 |
| Safety statements (S) | 26-27-28-36/37/39-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Desyl bromide used for?
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Desyl bromide is primarily used as a building block in organic synthesis, including the preparation of phosphate esters and in the development of chemiluminogenic reactions for peptide analysis.
What is the CAS number and formula for Desyl bromide?
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The CAS number for Desyl bromide is 1484-50-0, and its linear formula is C6H5CH(Br)COC6H5.
What is the grade and purity of Desyl bromide offered by TSS?
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The Desyl bromide supplied by TSS has an assay of 97%.
What are the main hazards associated with Desyl bromide?
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Desyl bromide is classified with Danger as a signal word. It causes severe skin burns and eye damage (H314) and may cause respiratory irritation (H335). Appropriate personal protective equipment, including eyeshields, face shields, and gloves, is essential.
How is Desyl bromide packed and shipped?
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Desyl bromide is shipped under UN 3261, Hazard Class 8, Packing Group II, indicating it is a corrosive solid, acidic, organic, n.o.s. It requires careful handling and appropriate transportation regulations.
How can I request a quote for Desyl bromide?
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To request a quote for Desyl bromide, please contact our sales department at TSS with your specific quantity requirements and delivery details.
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