Derivatized Silica Gel
Derivatized Silica Gel (CAS: 66369-14-0) is a specially modified silica-based stationary phase widely employed in chromatography. With a typical carbon loading of ~12%, a pore size of 60 Å, a surface area of 500 m²/g, and a mean particle size of 15-40 µm, it offers excellent separation capabilities for various analytical and preparative applications. This material is crucial for chemical synthesis support and in the development of robust LC separation media.

High-Performance Liquid Chromatography (HPLC)
Utilised as a stationary phase in reversed-phase HPLC for the separation of a wide range of organic compounds. Its C18 derivatization provides hydrophobic interaction suitable for analysing diverse analytes.
Solid-Phase Extraction (SPE)
Serves as an effective sorbent in SPE cartridges for sample pre-concentration and purification. It allows for selective retention and elution of target compounds from complex matrices.
Chromatographic Media
As a form of modified silica gel, it functions as a versatile medium for both analytical and preparative chromatography, offering reliable and reproducible separation performance.
Chemical Synthesis Support
Can be employed in solid-supported synthesis strategies, providing a stable matrix for immobilising reagents or facilitating reaction work-ups.
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Water hazard class (WGK, DE) | 3 |
|---|---|
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20-36/37 |
| Safety statements (S) | 22-26-36 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Extent Of Labeling | ~12% carbon loading |
|---|---|
| Pore Size | 60 |
| Surface Area | 500 m2/g |
| Mean Particle Size | 15-40 μm |
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Derivatized Silica Gel used for?
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Derivatized Silica Gel (CAS: 66369-14-0) is primarily used as a stationary phase in chromatography, including HPLC and SPE, for the separation and purification of chemical compounds. It also finds application in chemical synthesis support.
What is the CAS number and chemical formula for Derivatized Silica Gel?
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The CAS number for Derivatized Silica Gel is 66369-14-0. A specific chemical formula is not applicable as it refers to a modified solid support.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Derivatized Silica Gel with specifications including ~12% carbon loading, 60 Å pore size, 500 m²/g surface area, and 15-40 µm particle size. This product is supplied for laboratory and industrial use and is not represented as USP, BP, EP, or any other pharmacopoeial grade.
How should Derivatized Silica Gel be handled safely?
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Handle Derivatized Silica Gel with care, avoiding inhalation of dust and contact with skin and eyes. Wear appropriate personal protective equipment, including gloves and eye protection. Ensure adequate ventilation. Refer to the Safety Data Sheet (SDS) for comprehensive safety information. This material is classified as harmful if inhaled and causes irritation to the respiratory tract and eyes.
How is Derivatized Silica Gel packed and shipped?
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Derivatized Silica Gel is carefully packed to ensure product integrity during transit and is exported globally by Tech Serve Solutions in compliance with international shipping regulations.
How can I request a quote or sample?
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To request a quote or a sample of Derivatized Silica Gel, please contact our sales team directly through the website or by phone, providing your specific requirements.
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