D-Norvaline
D-Norvaline (CAS: 2013-12-9), a non-proteinogenic alpha-amino acid with the linear formula CH3CH2CH2CH(NH2)CO2H and a molecular weight of 117.15 g/mol, is a vital chiral building block. It is primarily utilised in chemical synthesis and peptide chemistry for the creation of unnatural peptides and complex organic molecules. Its specific stereochemistry and functional groups make it a valuable intermediate in advanced chemical research and development.
- IUPAC
- (R)-(−)-2-Aminopentanoic acid
Chemical Synthesis
D-Norvaline serves as a chiral synthon in the construction of complex organic molecules. Its defined stereochemistry is crucial for stereoselective synthesis pathways in pharmaceutical and fine chemical research.
Peptide Chemistry
As an unnatural amino acid, D-Norvaline is incorporated into peptides to modify their structure and properties. This can lead to peptides with enhanced stability, altered biological activity, or novel therapeutic potential.
Biochemical Research
This compound finds application in chemical biology studies, contributing to the understanding of enzyme mechanisms and protein-ligand interactions. It is used to explore the effects of non-natural amino acid residues in biological systems.
Derivative Synthesis
D-Norvaline acts as a precursor for the synthesis of various norvaline derivatives. These derivatives can be further investigated for diverse chemical and biological applications.
| Molecular weight | 117.15 |
|---|---|
| Linear formula | CH3CH2CH2CH(NH2)CO2H |
| Assay | 99% |
| Optical activity | [α]20/D −24°, c = 10 in 5 M HCl |
| Optical purity | ee: 98% (GLC) |
| Melting point | >300 °C(lit.) |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Norvaline used for?
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D-Norvaline is primarily used in chemical synthesis and peptide chemistry, particularly for creating unnatural peptides and as a chiral building block in organic synthesis. It is also employed in chemical biology research.
What is the CAS number and formula for D-Norvaline?
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The CAS number for D-Norvaline is 2013-12-9, and its linear formula is CH3CH2CH2CH(NH2)CO2H.
What grade and purity does Tech Serve Solutions supply for D-Norvaline?
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Tech Serve Solutions supplies D-Norvaline with an assay of 99%. It exhibits optical activity of [α]20/D −24°, c = 10 in 5 M HCl, and an optical purity of ee: 98% (GLC). This product is supplied for research and chemical synthesis purposes and is not represented as USP, BP, EP, or pharmacopoeia grade.
How should D-Norvaline be handled safely?
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Handling D-Norvaline requires appropriate personal protective equipment, including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter is recommended. It is classified under WGK 2 in Germany.
Is D-Norvaline a controlled substance?
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The provided data does not indicate that D-Norvaline (CAS: 2013-12-9) is a controlled substance.
How is D-Norvaline shipped by Tech Serve Solutions?
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Tech Serve Solutions exports and ships fine chemicals globally. Specific packaging and shipping details for D-Norvaline will be provided upon request and in compliance with international regulations.
How can I request a sample or quote for D-Norvaline?
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To request a sample or a quotation for D-Norvaline, please contact our sales team through the official Tech Serve Solutions website, providing your specific requirements and contact information.
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