D-Penicillamine
D-Penicillamine (CAS: 52-67-5) is a chiral thiol-containing amino acid. It is the D-enantiomer of penicillamine and is known for its chelating properties, as well as its role in breaking disulfide bonds. This compound is primarily utilized in research settings for its biochemical and chemical properties, often as a reagent in laboratory synthesis and biological studies.
- IUPAC
- 3,3-Dimethyl-D-cysteine,3-Mercapto-D-valine,D-(−)-2-Amino-3-mercapto-3-methylbutanoic acid
- Synonyms
- 3,3-Dimethyl-D-cysteine3-Mercapto-D-valineD-(−)-2-Amino-3-mercapto-3-methylbutanoic acid
Chelating Agent in Research
D-Penicillamine serves as a valuable chelating agent in biochemical research, capable of binding to various metal ions. This property makes it useful for studying metal ion metabolism and developing experimental models.
Disulfide Bond Cleavage
The thiol group in D-Penicillamine can readily react with disulfide bonds, leading to their cleavage. This characteristic is leveraged in studies of protein structure and function, particularly in understanding disulfide bond dynamics.
Reagent in Chemical Synthesis
As a unique amino acid derivative, D-Penicillamine is employed as a building block or reagent in complex organic synthesis pathways within research laboratories.
| Molecular weight | 149.21 |
|---|---|
| Linear formula | (CH3)2C(SH)CH(NH2)CO2H |
| Assay | ≥99.0% (NT) |
| Optical activity | [α]20/D −63±2°, c = 1% in 1 M NaOH |
| Melting point | 210 °C (dec.)(lit.)214-217 °C (dec.) |
Hazard statements
- H315Causes skin irritation
- H319Causes serious eye irritation
- H335May cause respiratory irritation
Precautionary statements
- P261Avoid breathing dust, fume, gas or vapours
- P305IF IN EYES
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Water hazard class (WGK, DE) | 2 |
| Hazard codes (EU) | Xi |
| Risk statements (R) | 36/37/38 |
| Safety statements (S) | 26-36 |
| Ignition residue | ≤0.05% |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | mouse ... Oprk1(18387) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Penicillamine used for?
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In research settings, D-Penicillamine is used for its chelating properties, to cleave disulfide bonds, and as a reagent in chemical synthesis.
What are the CAS number and formula for D-Penicillamine?
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The CAS number for D-Penicillamine is 52-67-5. Its linear formula is (CH₃)₂C(SH)CH(NH₂)CO₂H.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Penicillamine with an assay of ≥99.0% (NT). We do not represent this product as USP, BP, EP, or any other pharmacopoeia grade.
How should D-Penicillamine be handled safely?
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D-Penicillamine is a Warning substance that causes skin irritation (H315), serious eye irritation (H319), and may cause respiratory irritation (H335). Always use appropriate personal protective equipment, including a dust mask (type N95 US), eyeshields, and gloves, and ensure adequate ventilation.
Is D-Penicillamine a controlled substance?
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The provided data does not indicate that D-Penicillamine is a controlled substance.
How is D-Penicillamine packed and shipped?
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D-Penicillamine is packed according to industry best practices for chemical reagents and is available for global export by Tech Serve Solutions.
How can I request a quote or sample for D-Penicillamine?
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Please contact our sales team through the website or by phone to request a quote or sample for D-Penicillamine.
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