D-Norleucine
D-Norleucine (CAS: 327-56-0), a non-proteinogenic alpha-amino acid with the molecular formula C6H13NO2, is a valuable chiral building block. It is distinguished by its six-carbon chain, making it an isomer of leucine and isoleucine. D-Norleucine finds application in research settings as a synthetic intermediate and as a tool in biochemical studies, particularly in the development of peptidomimetics and peptide-based therapeutics.
- IUPAC
- (R)-2-Aminocaproic acid,(R)-2-Aminohexanoic acid
- Synonyms
- (R)-2-Aminocaproic acid(R)-2-Aminohexanoic acid

Chemical Synthesis
D-Norleucine serves as a chiral building block in organic synthesis, enabling the construction of complex molecules with defined stereochemistry. Its structure is useful for creating analogues of natural peptides.
Biochemical Research
Utilised in biochemical investigations, D-Norleucine can be incorporated into peptides to study their structure-activity relationships or as a tool to probe enzyme mechanisms. It is particularly relevant in the development of unnatural amino acid-based compounds.
Peptidomimetics Development
As an unnatural amino acid, D-Norleucine is employed in the design and synthesis of peptidomimetics, which are compounds that mimic the biological activity of peptides but often possess improved stability and bioavailability.
| Molecular weight | 131.17 |
|---|---|
| Empirical formula | C6H13NO2 |
| Protective equipment | Eyeshields, Gloves, type N95 (US), type P1 (EN143) respirator filter |
|---|---|
| Water hazard class (WGK, DE) | 3 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is D-Norleucine used for?
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D-Norleucine is used as a chiral building block in chemical synthesis and for biochemical research, including the development of peptidomimetics and peptide-based therapeutics.
What are the CAS number and chemical formula for D-Norleucine?
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The CAS number for D-Norleucine is 327-56-0, and its chemical formula is C6H13NO2.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies D-Norleucine as a research chemical. The specific assay and purity are detailed in the product's Certificate of Analysis. We do not represent this product as USP, BP, EP, or food grade unless explicitly stated.
How should D-Norleucine be handled safely?
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D-Norleucine is classified with WGK Germany of 3. Handle with care, using appropriate personal protective equipment including eyeshields and gloves. A type N95 (US) or type P1 (EN143) respirator filter may be necessary.
Is D-Norleucine a controlled substance?
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The provided data does not indicate that D-Norleucine is a controlled substance.
How is D-Norleucine packed, shipped, and exported?
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D-Norleucine is carefully packed according to industry standards for safe transport. Tech Serve Solutions has extensive experience in exporting chemicals globally, ensuring compliance with all relevant shipping regulations.
How can I request a sample or quote for D-Norleucine?
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To request a sample or a quotation for D-Norleucine, please contact our sales team through the website or by phone, providing your specific requirements.
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