Colchicine
Colchicine (CAS: 64-86-8) is a potent alkaloid with the chemical formula C22H25NO6 and a molecular weight of 399.44 g/mol. Primarily known for its anti-inflammatory properties, it acts as a microtubule-destabilising agent. It is widely employed in biochemical research for studying cell division and is a critical reagent in cell biology and enzyme inhibition studies. Available from TSS with an assay of ≥96.0% (HPLC).
Cell Biology Research
Colchicine is extensively used in cell biology to investigate the role of microtubules in cellular processes such as mitosis and cell motility. Its ability to disrupt microtubule polymerization makes it a valuable tool for studying chromosome segregation and cellular structure.
Enzyme Inhibition Studies
As an enzyme inhibitor, Colchicine is utilised in biochemical research to probe the mechanisms of various enzymatic pathways. It serves as a reference compound in studies related to protein function and cellular signaling cascades.
Biochemical Reagent
This compound functions as a significant biochemical reagent for research purposes. Its well-defined activity profile aids in understanding complex biological systems and developing new research methodologies.
| Molecular weight | 399.44 |
|---|---|
| Empirical formula | C22H25NO6 |
| Assay | ≥96.0% (HPLC) |
| Impurities tested | ≤10% ethyl acetate + H2O≤3% water |
| Melting point | 150-160 °C (dec.)(lit.) |
Hazard statements
- H300Fatal if swallowed
- H318Causes serious eye damage
- H340May cause genetic defects
Precautionary statements
- P201Obtain special instructions before use
- P260Do not breathe dust, fume, gas, mist, vapours or spray
- P264Wash thoroughly after handling
- P280Wear protective gloves, clothing and eye/face protection
- P284Wear respiratory protection
- P301IF SWALLOWED
| Protective equipment | Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges |
|---|---|
| Transport (UN / ADR) | UN 1544PSN1 6.1 / PGI |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | T+ |
| Risk statements (R) | 46-28 |
| Safety statements (S) | 53-45 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is Colchicine used for?
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Colchicine is used in biochemical research for studying cell division, microtubule dynamics, and enzyme inhibition. It is a valuable tool in cell biology and related scientific investigations.
What are the CAS number and formula for Colchicine?
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The CAS number for Colchicine is 64-86-8, and its chemical formula is C22H25NO6.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies Colchicine with an assay of ≥96.0% (HPLC). TSS does not represent this product as USP, BP, or EP grade.
How should Colchicine be handled safely?
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Colchicine is a dangerous substance. Handle with extreme caution, using appropriate personal protective equipment including eyeshields, faceshields, gloves, and respiratory protection (N100 or P3 rated). Avoid inhalation, ingestion, and contact. Refer to the safety data sheet for full handling instructions.
Is Colchicine a controlled substance?
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The provided data does not indicate that Colchicine is a controlled substance. However, users should verify local regulations.
How is Colchicine packed and exported?
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Colchicine is carefully packed according to regulatory standards for safe transport and export. Specific packaging details are available upon request.
How can I request a quote or sample of Colchicine?
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To request a quote or sample of Colchicine, please contact our sales team through the TSS website or your designated account manager.
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