cis-(Z)-Flupenthixol dihydrochloride
cis-(Z)-Flupenthixol dihydrochloride (CAS: 51529-01-2) is a trifluoromethyl-substituted thioxanthene derivative with the molecular formula C23H25F3N2OS · 2HCl and a molecular weight of 507.44. This white to off-white solid is primarily utilized as a research chemical, particularly in neuroscience, due to its activity as a dopaminergic antagonist. It serves as a valuable tool in studies investigating dopamine receptor function and signaling pathways.
- IUPAC
- (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride,Flupentixol dihydrochloride
- Synonyms
- (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride,Flupentixol dihydrochloride

Neuroscience Research
Utilized in scientific research to investigate the dopaminergic system, including dopamine receptor binding and signaling pathways. It acts as a tool for understanding neurotransmission.
Dopamine Receptor Antagonism Studies
Serves as a selective antagonist for dopamine receptors (DRD1-5), making it valuable for in vitro and in vivo research exploring the physiological roles of these receptors.
Pharmacological Research
Employed in drug discovery and development research as a reference compound or a tool to probe the mechanisms of action of new therapeutic candidates targeting dopaminergic pathways.
| Molecular weight | 507.44 |
|---|---|
| Empirical formula | C23H25F3N2OS · 2HCl |
| Assay | ≥98% (HPLC) |
| Form | solid |
| Colour | white to off-white |
| Solubility | H2O: soluble |

Hazard statements
- H302Harmful if swallowed
- H312Harmful in contact with skin
- H332Harmful if inhaled
Precautionary statements
- P280Wear protective gloves, clothing and eye/face protection
| Protective equipment | dust mask type N95 (US), Eyeshields, Gloves |
|---|---|
| Transport (UN / ADR) | UN 2811 6.1 / PGIII |
| Water hazard class (WGK, DE) | 3 |
| Hazard codes (EU) | Xn |
| Risk statements (R) | 20/21/22 |
| Safety statements (S) | 36/37/39 |
Hazard information is provided for guidance. Always consult the product Safety Data Sheet (SDS), available on request, before handling.
| Gene Information | human ... DRD1(1812), DRD2(1813), DRD3(1814), DRD4(1815), DRD5(1816) |
|---|
Documentation
Every batch ships with a Certificate of Analysis covering assay, identity and purity; the grade is confirmed against your enquiry. Safety Data Sheets and technical data sheets are available on request.
Supply & logistics
Samples for technical evaluation; bulk MOQ by grade and packaging. In-stock material ships in 7–10 working days, worldwide, with full export documentation.
What is cis-(Z)-Flupenthixol dihydrochloride used for?
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cis-(Z)-Flupenthixol dihydrochloride is primarily used in neuroscience and pharmacological research as a dopaminergic antagonist to study dopamine receptor function and signaling pathways.
What is the CAS number and formula for cis-(Z)-Flupenthixol dihydrochloride?
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The CAS number is 51529-01-2 and the empirical formula is C23H25F3N2OS · 2HCl.
What grade and purity does Tech Serve Solutions supply?
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Tech Serve Solutions supplies cis-(Z)-Flupenthixol dihydrochloride with an assay of ≥98% (HPLC). This product is intended for research purposes only and is not represented as USP, BP, or EP grade.
How should cis-(Z)-Flupenthixol dihydrochloride be handled safely?
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This compound is harmful if swallowed, in contact with skin, or if inhaled (H302-H312-H332). Handle with appropriate personal protective equipment, including a dust mask (N95), eyeshields, and gloves, in a well-ventilated area.
Is cis-(Z)-Flupenthixol dihydrochloride a controlled substance?
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This information is not available in the provided data. Please consult relevant local regulations for controlled substance status.
How is cis-(Z)-Flupenthixol dihydrochloride packed, shipped, and exported?
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cis-(Z)-Flupenthixol dihydrochloride is shipped as a solid, white to off-white powder. It is classified under UN 2811, Class 6.1, Packing Group III, for international transport.
How can I request a sample or quote for cis-(Z)-Flupenthixol dihydrochloride?
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To request a sample or a quote, please contact the Tech Serve Solutions sales team through our website or by phone, providing the product name and CAS number.
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